Oxycontin and Nitrolingual drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Oxycontin (oxycodone hydrochloride) and Nitrolingual (nitroglycerin). Common drug interactions include gastritis among females and fall among males.
The phase IV clinical study analyzes what interactions people have when they take Oxycontin and Nitrolingual. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.
What is Oxycontin?
Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.
What is Nitrolingual?
Nitrolingual has active ingredients of nitroglycerin. eHealthMe is studying from 2,777 Nitrolingual users. Check the latest studies of Nitrolingual.
47 people who take Oxycontin and Nitrolingual together, and have interactions are studied.

What are the common drug interactions of Oxycontin and Nitrolingual, by gender? *:
female:
- Gastritis (inflammation of stomach)
- Generalised erythema (redness of the skin all over the body)
- Glaucoma (increased fluid pressure in the eye with vision loss)
- Hallucination (an experience involving the perception of something not present)
- Hypersensitivity
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
- Hypotension (abnormally low blood pressure)
- Insomnia (sleeplessness)
- Iron deficiency
- Joint injury
male:
- Fall
- Hip fracture
- Rectal haemorrhage (bleeding from anus)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cardiac disorder
- Femoral neck fracture (neck of femur bone fracture)
- Flushing (the warm, red condition of human skin)
- Hyperhidrosis (abnormally increased sweating)
- Influenza
- Malignant neoplasm progression (cancer tumour came back)
What are the common drug interactions of Oxycontin and Nitrolingual, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Diarrhoea
- Flushing (the warm, red condition of human skin)
- Hyperhidrosis (abnormally increased sweating)
- Influenza
- Pyrexia (fever)
- Abdominal pain
- Anaemia (lack of blood)
- Blood pressure decreased
- Leukocytosis (increased white blood cells)
- Pancreatitis (inflammation of pancreas)
50-59:
- Sleep disorder
- Swollen tongue (swelling of tongue)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Weight decreased
- Wheezing (a high-pitched whistling sound made while you breath)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Hypertension (high blood pressure)
- Malignant neoplasm progression (cancer tumour came back)
- Memory impairment
- Urticaria (rash of round, red welts on the skin that itch intensely)
60+:
- Fall
- Pneumonia
- Rectal haemorrhage (bleeding from anus)
- Cardiac disorder
- Cardiac failure
- Drug ineffective
- Fatigue (feeling of tiredness)
- Femoral neck fracture (neck of femur bone fracture)
- Nausea (feeling of having an urge to vomit)
- Oedema peripheral (superficial swelling)
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 10 people, 21.28%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 19.15%
- Chest Pain: 7 people, 14.89%
- Anaemia (lack of blood): 6 people, 12.77%
- High Blood Pressure: 5 people, 10.64%
- Asthma: 5 people, 10.64%
- Dyspnea (difficult or laboured breathing): 4 people, 8.51%
- Fever: 4 people, 8.51%
- Urinary Tract Infection: 4 people, 8.51%
- Insomnia (sleeplessness): 4 people, 8.51%
* Approximation only. Some reports may have incomplete information.
Do you take Oxycontin and Nitrolingual?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Oxycontin (212,533 reports)
- Nitrolingual (2,777 reports)
Browse all drug interactions of Oxycontin and Nitrolingual:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Oxycontin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nitrolingual:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Oxycontin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nitrolingual and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on oxycodone hydrochloride and nitroglycerin (the active ingredients of Oxycontin and Nitrolingual, respectively), and Oxycontin and Nitrolingual (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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