Oxycontin and Tarka drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycontin (oxycodone hydrochloride) and Tarka (trandolapril; verapamil hydrochloride). Common drug interactions include asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycontin and Tarka. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.

What is Tarka?

Tarka has active ingredients of trandolapril; verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,409 Tarka users. Check the latest studies of Tarka.

On Jul, 18, 2026

13 people who take Oxycontin and Tarka together, and have interactions are studied.

What are the common drug interactions of Oxycontin and Tarka, by gender? *:

female:

n/a

male:

Asthenia (weakness)
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)
Respiratory disorder (respiratory disease)
Thrombocytopenia (decrease of platelets in blood)
Abdominal pain lower
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arrhythmia (irregular heartbeat)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

What are the common drug interactions of Oxycontin and Tarka, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dysstasia (difficulty in standing)
Haemorrhagic diathesis (bleeding tendency)
Hepatosplenic t-cell lymphoma (neoplasm comprising medium-sized cytotoxic t-cells that show a significant sinusoidal infiltration in the liver, spleen, and bone marrow)
Mucosal inflammation (infection of mucous membrane)
Neutropenia (an abnormally low number of neutrophils)
Pain in extremity
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

50-59:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
Deafness bilateral
Diarrhoea
Hallucination, visual (seeing things that aren't there)
Nausea (feeling of having an urge to vomit)
Rash

60+:

Asthenia (weakness)
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)
Respiratory disorder (respiratory disease)
Thrombocytopenia (decrease of platelets in blood)
Abdominal pain lower
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arrhythmia (irregular heartbeat)
Cardiac arrest
Cardiac failure congestive
Cough

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 2 people, 15.38%
Depression: 2 people, 15.38%
Musculoskeletal Disorder (disease of the body's muscles, joints, tendons, ligaments and nerves): 2 people, 15.38%
Joint Pain: 1 person, 7.69%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 7.69%
Erysipelas (bacterial skin infection): 1 person, 7.69%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
Herpes Virus Infection: 1 person, 7.69%
High Blood Cholesterol: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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