Ozempic and Prochlorperazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ozempic (semaglutide) and Prochlorperazine (prochlorperazine). Common drug interactions include agitation among females and blood pressure increased among males.

The phase IV clinical study analyzes what interactions people have when they take Ozempic and Prochlorperazine. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Ozempic?

Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,762 Ozempic users. Check the latest studies of Ozempic.

What is Prochlorperazine?

Prochlorperazine has active ingredients of prochlorperazine. It is often used in nausea. eHealthMe is studying from 14,632 Prochlorperazine users. Check the latest studies of Prochlorperazine.

On Aug, 12, 2026

58 people who take Ozempic and Prochlorperazine together, and have interactions are studied.

Ozempic and Prochlorperazine drug interactions.

What are the common drug interactions of Ozempic and Prochlorperazine, by gender? *:

female:

Agitation (state of anxiety or nervous excitement)
Asthenia (weakness)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Discomfort
Ear infection
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Headache (pain in head)
Hypersomnia (excessive daytime sleepiness (eds))
Hypoaesthesia (reduced sense of touch or sensation)

male:

Blood pressure increased
Hospitalisation
Constipation
Fall
Haemorrhage intracranial (bleeding within the skull)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pruritus (severe itching of the skin)
Pyrexia (fever)

What are the common drug interactions of Ozempic and Prochlorperazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Groin infection (infection in groin)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Sepsis (a severe blood infection that can lead to organ failure and death)
Soft tissue infection
Anal abscess
Anxiety
Depression
Genital abscess (build up of pus in genital)
Pruritus (severe itching of the skin)

30-39:

Fatigue (feeling of tiredness)
Muscle spasms (muscle contraction)
Dyspnoea (difficult or laboured respiration)
Discomfort
Hypoaesthesia (reduced sense of touch or sensation)
Lymph gland infection
Oropharyngeal pain
Pain in extremity
Skin infection
Skin ulcer

40-49:

Abdominal discomfort
Aggression
Agitation (state of anxiety or nervous excitement)
Anxiety
Asthenia (weakness)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Ear infection
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)

50-59:

Constipation
Cough
Disease progression
Dysphonia (speech disorder attributable to a disorder of phonation)
Fatigue (feeling of tiredness)
Insomnia (sleeplessness)
Nail infection
Nasal septum deviation (deviated nasal septum)
Prostatic specific antigen increased
Prostatitis (inflammation of the prostate gland)

60+:

Vomiting
Diarrhoea
Glomerular filtration rate decreased
Gout (uric acid crystals building up in the body)
Oral pain
Oropharyngeal pain
Peripheral swelling
Rash macular (small, flat red spots)
Constipation
Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 7 people, 12.07%
Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 6.90%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 6.90%
Type 2 Diabetes: 3 people, 5.17%
Renal Cell Carcinoma (a kidney cancer): 3 people, 5.17%
Pain: 3 people, 5.17%
Nausea And Vomiting: 3 people, 5.17%
Immunodeficiency Common Variable: 3 people, 5.17%
Diabetes: 3 people, 5.17%

* Approximation only. Some reports may have incomplete information.

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