Ozempic and Soliris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ozempic (semaglutide) and Soliris (eculizumab). Common drug interactions include anxiety among females and erythema among males.

The phase IV clinical study analyzes what interactions people have when they take Ozempic and Soliris. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Ozempic?

Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,762 Ozempic users. Check the latest studies of Ozempic.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

12 people who take Ozempic and Soliris together, and have interactions are studied.

What are the common drug interactions of Ozempic and Soliris, by gender? *:

female:

Anxiety
Arthralgia (joint pain)
Back pain
Cataract (clouding of the lens inside the eye)
Constipation
Cough
Depression
Dizziness
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)

male:

Erythema (redness of the skin)
Pain in extremity
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Dizziness
Dysgeusia (disorder of the sense of taste)
Erectile dysfunction
Influenza
Headache (pain in head)
Nasopharyngitis (inflammation of the nasopharynx)
Asthenia (weakness)

What are the common drug interactions of Ozempic and Soliris, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abscess (pus)
Arteriovenous fistula
Arthralgia (joint pain)
Decreased immune responsiveness
Dizziness
Erectile dysfunction
Influenza

60+:

Anxiety
Arthralgia (joint pain)
Fatigue (feeling of tiredness)
Headache (pain in head)
Incontinence (lack of moderation or self-control)
Nausea (feeling of having an urge to vomit)
Oedema (fluid collection in tissue)
Pain in extremity
Poor venous access
Rash

What are the existing conditions these people have? *

Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 7 people, 58.33%
Diabetes: 5 people, 41.67%
Blood Calcium Decreased: 5 people, 41.67%
Renal Disorder (kidney disease): 4 people, 33.33%
High Blood Cholesterol: 4 people, 33.33%
Blood Glucose Abnormal: 4 people, 33.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%
Gastric Ph Decreased: 2 people, 16.67%
Calcium Deficiency (lack of calcium): 2 people, 16.67%
Blood Glucose Increased: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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