Ozempic and Vumerity drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ozempic (semaglutide) and Vumerity (diroximel fumarate). Common drug interactions include flushing among females and abdominal discomfort among males.
The phase IV clinical study analyzes what interactions people have when they take Ozempic and Vumerity. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.
What is Ozempic?
Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,761 Ozempic users. Check the latest studies of Ozempic.
What is Vumerity?
Vumerity has active ingredients of diroximel fumarate. eHealthMe is studying from 9,781 Vumerity users. Check the latest studies of Vumerity.
35 people who take Ozempic and Vumerity together, and have interactions are studied.

What are the common drug interactions of Ozempic and Vumerity, by gender? *:
female:
- Flushing (the warm, red condition of human skin)
- Nausea (feeling of having an urge to vomit)
- Pruritus (severe itching of the skin)
- Muscular weakness (muscle weakness)
- Abdominal pain upper
- Memory impairment
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Vomiting
- Pain in extremity
- Blood glucose decreased
male:
- Abdominal discomfort
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Diabetic ulcer
- Infected skin ulcer
- Cataract (clouding of the lens inside the eye)
- Diabetic foot
- General physical health deterioration (weak health status)
- Headache (pain in head)
- Peroneal nerve palsy
- Primary progressive multiple sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged)
What are the common drug interactions of Ozempic and Vumerity, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal pain upper
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Flushing (the warm, red condition of human skin)
- Gastric disorder (disease of stomach)
- Headache (pain in head)
- Heart rate increased
- Hypertension (high blood pressure)
- Nausea (feeling of having an urge to vomit)
- Aphthous ulcer (mouth ulcer)
- Oedema (fluid collection in tissue)
50-59:
- Abdominal discomfort
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cardiac flutter (abnormal heart rhythm)
- Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
- Fall
- Joint injury
- Limb injury
- Neuropathy peripheral (surface nerve damage)
- Tendon rupture (tear of tendon)
- Memory impairment
60+:
- Asthenia (weakness)
- Blood glucose decreased
- Pain in extremity
- Peripheral swelling
- Pruritus (severe itching of the skin)
- Type 2 diabetes mellitus
- Vomiting
- Diabetic foot
- Diabetic ulcer
- Infected skin ulcer
What are the existing conditions these people have? *
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 34 people, 97.14%
- Diabetes: 3 people, 8.57%
* Approximation only. Some reports may have incomplete information.
Do you take Ozempic and Vumerity?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ozempic and Vumerity:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ozempic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vumerity:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ozempic and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vumerity and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on semaglutide and diroximel fumarate (the active ingredients of Ozempic and Vumerity, respectively), and Ozempic and Vumerity (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Kesimpta cause Cellulitis? - 7 seconds ago
- Could Vitamin B2 cause Ileitis Aggravated? - 11 seconds ago
- Could Dulcolax cause Seborrhoeic Dermatitis? - 12 seconds ago
- Could Kayexalate cause Cellulitis? - 19 seconds ago
- Could Zaroxolyn cause Cellulitis? - 24 seconds ago
- Could Pantoprazole cause Otitis Externa? - 25 seconds ago
- Could Zemplar cause Cellulitis? - 32 seconds ago
- Could Zidovudine cause Cellulitis? - 33 seconds ago
- Otezla vs. Piroxicam, side effect and effectiveness comparison - 36 seconds ago
- Could Zonisamide cause Cellulitis? - 40 seconds ago