Pacerone and Cleocin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pacerone (amiodarone hydrochloride) and Cleocin (clindamycin phosphate). Common drug interactions include hyperbilirubinaemia among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Pacerone and Cleocin. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Pacerone?

Pacerone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,814 Pacerone users. Check the latest studies of Pacerone.

What is Cleocin?

Cleocin has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 3,940 Cleocin users. Check the latest studies of Cleocin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

25 people who take Pacerone and Cleocin together, and have interactions are studied.

What are the common drug interactions of Pacerone and Cleocin, by gender? *:

female:

Hyperbilirubinaemia (excess of bilirubin in the blood)
Multi-organ failure (multisystem organ failure)
Pancreatitis (inflammation of pancreas)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Septic shock (shock due to blood infection)
Splenic abscess (pus in spleen or near by)
Anaemia (lack of blood)
Anxiety

male:

Cardiac failure congestive
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Cardiomyopathy (weakening of the heart muscle)
Cataract (clouding of the lens inside the eye)
Compression fracture (fracture due to pressure caused by injury)
Cough
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Disability
Dysphonia (speech disorder attributable to a disorder of phonation)

What are the common drug interactions of Pacerone and Cleocin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Actinic keratosis (skin disease due to sun exposure)
Arteriosclerosis (thickening and hardening of arteries)
Cardiac failure congestive
Chapped lips (cracking, fissuring, and peeling of the skin f lip)
Chronic kidney disease
Colon cancer
Gangrene (body tissue dies)
Hypertension (high blood pressure)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)

50-59:

Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Osteonecrosis (death of bone)
Skin ulcer
Stasis dermatitis (skin inflammation caused by blood pooling in the veins in your legs)
Actinic keratosis (skin disease due to sun exposure)
Cardiac failure congestive
Chapped lips (cracking, fissuring, and peeling of the skin f lip)
Chronic kidney disease
Colon cancer
Gangrene (body tissue dies)

60+:

Hypertension (high blood pressure)
Cardiac failure congestive
Cough
Addison's disease (addison's disease, a hormonal disorder disease)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Atelectasis (partial or complete collapse of the lung)
Cardiomyopathy (weakening of the heart muscle)
Cataract (clouding of the lens inside the eye)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Compression fracture (fracture due to pressure caused by injury)

What are the existing conditions these people have? *

Prostate Cancer Metastatic: 10 people, 40.00%
Cardiac Disorder: 4 people, 16.00%
Type 2 Diabetes: 3 people, 12.00%
Pain: 3 people, 12.00%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 3 people, 12.00%
Weight Decreased: 2 people, 8.00%
Stress And Anxiety: 2 people, 8.00%
Sedation: 2 people, 8.00%
Rashes (redness): 2 people, 8.00%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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