Pacerone and Torsemide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pacerone (amiodarone hydrochloride) and Torsemide (torsemide). Common drug interactions include dizziness among females and cardiac failure congestive among males.
The phase IV clinical study analyzes what interactions people have when they take Pacerone and Torsemide. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.
What is Pacerone?
Pacerone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,814 Pacerone users. Check the latest studies of Pacerone.
What is Torsemide?
Torsemide has active ingredients of torsemide. It is often used in high blood pressure. eHealthMe is studying from 33,072 Torsemide users. Check the latest studies of Torsemide.
65 people who take Pacerone and Torsemide together, and have interactions are studied.

What are the common drug interactions of Pacerone and Torsemide, by gender? *:
female:
- Dizziness
- Dyspnoea exertional (breathlessness or shortness of breath)
- Dysuria (painful or difficult urination)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Hypophagia (reduced food intake)
- Hypotension (abnormally low blood pressure)
- Hypoxia (low oxygen in tissues)
- Mineral supplementation
- Oedema (fluid collection in tissue)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
male:
- Cardiac failure congestive
- Renal failure acute (rapid kidney dysfunction)
- Cardiac failure
- Cholecystitis acute (rapid infection of gallbladder)
- Exercise tolerance decreased
- Hepatojugular reflux (a venous reflux occurring in congestive heart failure)
- Hypokalaemia (low potassium)
- Loss of consciousness
- Multiple injuries
- Pulmonary congestion (congestion in the lungs)
What are the common drug interactions of Pacerone and Torsemide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Hypotension (abnormally low blood pressure)
- Dizziness
- Renal failure acute (rapid kidney dysfunction)
- Aortic valve calcification
- Atrioventricular block first degree (heart block first degree)
- Cardiac failure
- Cholecystitis acute (rapid infection of gallbladder)
- Exercise tolerance decreased
- Hepatojugular reflux (a venous reflux occurring in congestive heart failure)
- Loss of consciousness
50-59:
- Blood potassium decreased
- Blood pressure decreased
- Blood uric acid increased
- Breath sounds
- Carbon dioxide increased
- Cardiac murmur (an heart sound in valve abnormality)
- Cardiomegaly (increased size of heart than normal)
- Cardiomyopathy (weakening of the heart muscle)
- Chapped lips (cracking, fissuring, and peeling of the skin f lip)
- Colon cancer
60+:
- Chronic kidney disease
- Rectal haemorrhage (bleeding from anus)
- Decreased appetite
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Pruritus (severe itching of the skin)
- Abdominal pain
- Abdominal pain upper
- Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 16.92%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 8 people, 12.31%
- Pain: 7 people, 10.77%
- Cardiac Failure Congestive: 7 people, 10.77%
- Infection: 5 people, 7.69%
- Hypokalemia (low potassium): 5 people, 7.69%
- High Blood Cholesterol: 5 people, 7.69%
- Diabetes: 5 people, 7.69%
- Constipation: 5 people, 7.69%
- Type 2 Diabetes: 4 people, 6.15%
* Approximation only. Some reports may have incomplete information.
Do you take Pacerone and Torsemide?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Pacerone and Torsemide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pacerone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Torsemide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pacerone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Torsemide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on amiodarone hydrochloride and torsemide (the active ingredients of Pacerone and Torsemide, respectively), and Pacerone and Torsemide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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