Palbociclib and Ranitidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Palbociclib (palbociclib) and Ranitidine (ranitidine). Common drug interactions include neutropenia among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Palbociclib and Ranitidine. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Palbociclib?

Palbociclib has active ingredients of palbociclib. eHealthMe is studying from 11,622 Palbociclib users. Check the latest studies of Palbociclib.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

On Aug, 08, 2026

34 people who take Palbociclib and Ranitidine together, and have interactions are studied.

Palbociclib and Ranitidine drug interactions.

What are the common drug interactions of Palbociclib and Ranitidine, by gender? *:

female:

Neutropenia (an abnormally low number of neutrophils)
Sepsis (a severe blood infection that can lead to organ failure and death)
Arthralgia (joint pain)
Oral herpes (viral infection of mouth)
Asthenia (weakness)
Anaemia (lack of blood)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Chest pain
Pain
Carbohydrate antigen 15-3 increased

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Fatigue (feeling of tiredness)
Full blood count decreased
Gait disturbance
Haemoglobin decreased
Leukopenia (less number of white blood cells in blood)
Lymphadenopathy (disease or enlargement of lymph nodes)
Malignant neoplasm progression (cancer tumour came back)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

What are the common drug interactions of Palbociclib and Ranitidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chest pain
Electrocardiogram t wave inversion
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

50-59:

Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Pain
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Asthenia (weakness)
Carbohydrate antigen 15-3 increased
Carcinoembryonic antigen increased
Leukopenia (less number of white blood cells in blood)
Neutropenia (an abnormally low number of neutrophils)
Platelet count decreased

60+:

Neutropenia (an abnormally low number of neutrophils)
Sepsis (a severe blood infection that can lead to organ failure and death)
Febrile neutropenia (fever with reduced white blood cells)
Interstitial lung disease
Pyelonephritis (inflammation of kidney caused by bacteria)
Anaemia (lack of blood)
Anxiety
Back pain
Bone marrow failure
Constipation

What are the existing conditions these people have? *

Breast Cancer: 9 people, 26.47%
Breast Cancer Metastatic: 7 people, 20.59%
Pain: 7 people, 20.59%
Stress And Anxiety: 6 people, 17.65%
Metastases To Bone (cancer spreads to bone): 6 people, 17.65%
Constipation: 6 people, 17.65%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 17.65%
Adverse Event: 5 people, 14.71%
Nausea (feeling of having an urge to vomit): 4 people, 11.76%
High Blood Pressure: 4 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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