Palladone and Revlimid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Palladone (hydromorphone hydrochloride) and Revlimid (lenalidomide). Common drug interactions include cardiac failure among females and hypocalcaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Palladone and Revlimid. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Palladone?
Palladone has active ingredients of hydromorphone hydrochloride. eHealthMe is studying from 2,546 Palladone users. Check the latest studies of Palladone.
What is Revlimid?
Revlimid has active ingredients of lenalidomide. It is often used in multiple myeloma. eHealthMe is studying from 378,026 Revlimid users. Check the latest studies of Revlimid.
32 people who take Palladone and Revlimid together, and have interactions are studied.

What are the common drug interactions of Palladone and Revlimid, by gender? *:
female:
- Cardiac failure
- Gastrointestinal stromal tumour (a cancer that arises from transformed cells of mesenchymal origin in gastrointestinal tract)
- Febrile neutropenia (fever with reduced white blood cells)
- General physical health deterioration (weak health status)
- Renal failure (kidney dysfunction)
- Appetite disorder (abnormal eating habits)
- Asthma
- Cough
- Drug ineffective
- Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
male:
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
- Cardiac failure
- Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
- Fatigue (feeling of tiredness)
- Hypokalaemia (low potassium)
- Inflammatory marker increased
- Cachexia (loss of weight)
- Gastric ulcer (stomach ulcer)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Osteosynthesis
What are the common drug interactions of Palladone and Revlimid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Cardiac failure
- Gastrointestinal stromal tumour (a cancer that arises from transformed cells of mesenchymal origin in gastrointestinal tract)
- Appetite disorder (abnormal eating habits)
- Asthma
- Cough
- Drug ineffective
- Febrile neutropenia (fever with reduced white blood cells)
- General physical health deterioration (weak health status)
- Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
- Overdose
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
- Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
- General physical health deterioration (weak health status)
- Bacterial infection
- Infection
- Lymphoma (cancer that begins in immune system cells)
- Sepsis (a severe blood infection that can lead to organ failure and death)
50-59:
- Bradycardia (abnormally slow heart action)
- Cardiovascular insufficiency (inadequate functioning of heart)
- Arthralgia (joint pain)
- Fatigue (feeling of tiredness)
- Vertigo
60+:
- Cardiac failure
- Confusional state
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
- General physical health deterioration (weak health status)
- Hypokalaemia (low potassium)
- Inflammatory marker increased
- Cachexia (loss of weight)
- Fatigue (feeling of tiredness)
- Gastric ulcer (stomach ulcer)
What are the existing conditions these people have? *
- High Blood Pressure: 8 people, 25.00%
- Osteoporosis (bones weak and more likely to break): 7 people, 21.88%
- Infection: 7 people, 21.88%
- Glaucoma (increased fluid pressure in the eye with vision loss): 7 people, 21.88%
- Myeloma Recurrence (recurrence of cancer of the plasma cells - a kind of white blood cell): 6 people, 18.75%
- Pain: 5 people, 15.62%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 12.50%
- Plasmacytoma (neoplasm of plasma cells (usually in bone marrow)): 3 people, 9.38%
- Febrile Neutropenia (fever with reduced white blood cells): 3 people, 9.38%
* Approximation only. Some reports may have incomplete information.
Do you take Palladone and Revlimid?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Palladone and Revlimid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Palladone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Revlimid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Palladone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Revlimid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on hydromorphone hydrochloride and lenalidomide (the active ingredients of Palladone and Revlimid, respectively), and Palladone and Revlimid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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