Palonosetron and Entecavir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Palonosetron (palonosetron hydrochloride) and Entecavir (entecavir). Common drug interactions include platelet count decreased among females and agitation among males.

The phase IV clinical study analyzes what interactions people have when they take Palonosetron and Entecavir. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Palonosetron?

Palonosetron has active ingredients of palonosetron hydrochloride. eHealthMe is studying from 5,962 Palonosetron users. Check the latest studies of Palonosetron.

What is Entecavir?

Entecavir has active ingredients of entecavir. It is often used in hepatitis b. eHealthMe is studying from 7,354 Entecavir users. Check the latest studies of Entecavir.



On Jul, 06, 2026

43 people who take Palonosetron and Entecavir together, and have interactions are studied.

Palonosetron and Entecavir drug interactions.

What are the common drug interactions of Palonosetron and Entecavir, by gender? *:

female:

  1. Platelet count decreased
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Compression fracture (fracture due to pressure caused by injury)
  4. Myelosuppression (a decrease in the production of blood cells)
  5. Bone marrow failure
  6. Nausea (feeling of having an urge to vomit)
  7. Neutropenia (an abnormally low number of neutrophils)
  8. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  9. Pyrexia (fever)
  10. Respiratory disorder (respiratory disease)

male:

  1. Agitation (state of anxiety or nervous excitement)
  2. Aphasia (damage to the parts of the brain that control language)
  3. White blood cell count decreased
  4. Anaemia (lack of blood)
  5. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  6. Intervertebral disc protrusion (spinal disc protrusion)
  7. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  8. Pyrexia (fever)
  9. Acute respiratory failure
  10. Decreased appetite

What are the common drug interactions of Palonosetron and Entecavir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Neutropenia (an abnormally low number of neutrophils)
  3. Compression fracture (fracture due to pressure caused by injury)
  4. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  5. Pyrexia (fever)
  6. Septic shock (shock due to blood infection)
  7. White blood cell count decreased
  8. Anaemia (lack of blood)
  9. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  10. Nausea (feeling of having an urge to vomit)

60+:

  1. Biliary tract infection
  2. Agitation (state of anxiety or nervous excitement)
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Leukopenia (less number of white blood cells in blood)
  5. Myelosuppression (a decrease in the production of blood cells)
  6. Intervertebral disc protrusion (spinal disc protrusion)
  7. Acute respiratory failure
  8. Bone marrow failure
  9. Decreased appetite
  10. Diarrhoea

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 15 people, 34.88%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 18.60%
  3. Pain: 8 people, 18.60%
  4. High Blood Pressure: 8 people, 18.60%
  5. Diabetes: 8 people, 18.60%
  6. Constipation: 7 people, 16.28%
  7. Nausea (feeling of having an urge to vomit): 7 people, 16.28%
  8. Fever: 6 people, 13.95%
  9. Diffuse Large B-Cell Lymphoma Refractory (cancer of b cells, a type of white blood cell-relapsed): 6 people, 13.95%
  10. White Blood Cell Count Increased: 6 people, 13.95%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Palonosetron and Entecavir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Palonosetron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Entecavir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Palonosetron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Entecavir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on palonosetron hydrochloride and entecavir (the active ingredients of Palonosetron and Entecavir, respectively), and Palonosetron and Entecavir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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