Pamelor and Viagra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pamelor (nortriptyline hydrochloride) and Viagra (sildenafil citrate). Common drug interactions include agitation among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Pamelor and Viagra. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Pamelor?

Pamelor has active ingredients of nortriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 4,069 Pamelor users. Check the latest studies of Pamelor.

What is Viagra?

Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.

On Jul, 20, 2026

24 people who take Pamelor and Viagra together, and have interactions are studied.

What are the common drug interactions of Pamelor and Viagra, by gender? *:

female:

Agitation (state of anxiety or nervous excitement)
Drug abuser
Drug toxicity
Hot flush (sudden feelings of heat)
Intervertebral disc protrusion (spinal disc protrusion)
Lacrimation increased
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Neck pain
Overdose
Pain in extremity

male:

Chronic kidney disease
Drug hypersensitivity
Nausea (feeling of having an urge to vomit)
Renal failure (kidney dysfunction)
Abdominal discomfort
Adverse event
Anxiety
Arthralgia (joint pain)
Bone spur (bony growth)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the common drug interactions of Pamelor and Viagra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal discomfort
Abdominal pain upper
Adverse event
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Drug dependence
Drug intolerance (drug sensitivity)
Dysphagia (a condition in which swallowing is difficult or painful)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haematochezia (passage of stools containing blood)
Nausea (feeling of having an urge to vomit)

40-49:

Renal tubular necrosis (death of kidney tubules)
Somnambulism (sleep walking)
Spinal fusion acquired
Spondylolisthesis acquired (self induced displacement of a vertebra or the vertebral column in relation to the vertebrae below)
Urinary tract infection
White blood cell count increased
Drug ineffective
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Emotional distress

50-59:

Joint contracture (a permanent shortening of a muscle or joint)
Muscle atrophy (a decrease in the mass of the muscle)
Neck pain
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Osteomyelitis (infection of bone)
Pain
Pain in extremity
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Skin ulcer

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Drug ineffective
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nephrogenic anaemia (anaemia due to kidney disease)

What are the existing conditions these people have? *

Pain: 12 people, 50.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 16.67%
High Blood Cholesterol: 3 people, 12.50%
Sleep Disorder: 2 people, 8.33%
Insomnia (sleeplessness): 2 people, 8.33%
Diabetes: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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