Pamidronate disodium and Doxorubicin hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pamidronate disodium (pamidronate disodium) and Doxorubicin hydrochloride (doxorubicin hydrochloride). Common drug interactions include breast cancer among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Pamidronate disodium and Doxorubicin hydrochloride. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Pamidronate disodium?

Pamidronate disodium has active ingredients of pamidronate disodium. eHealthMe is studying from 5,200 Pamidronate disodium users. Check the latest studies of Pamidronate disodium.

What is Doxorubicin hydrochloride?

Doxorubicin hydrochloride has active ingredients of doxorubicin hydrochloride. eHealthMe is studying from 25,343 Doxorubicin hydrochloride users. Check the latest studies of Doxorubicin hydrochloride.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

20 people who take Pamidronate disodium and Doxorubicin hydrochloride together, and have interactions are studied.

Pamidronate disodium and Doxorubicin hydrochloride drug interactions.

What are the common drug interactions of Pamidronate Disodium and Doxorubicin Hydrochloride, by gender? *:

female:

Breast cancer
Neoplasm progression (growth of tumour)
Second primary malignancy (after getting cure a cancer, a new cancer development)
Depression
Difficulty in walking
Faecal incontinence (a lack of control over passing stool)
Fall
Fatigue (feeling of tiredness)
Malignant neoplasm progression (cancer tumour came back)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

male:

Cardiac arrest
Discomfort
Pain in extremity
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Skin fibrosis (fibrous tissue formation on skin)
Skin induration (an abnormally hard spot or area on the skin)
Skin tightness
Subcutaneous nodule
Xerosis (abnormal dryness of the skin or mucus membranes)
Endocardial fibrosis (cardiac fibrosis refers to an abnormal thickening of the heart valves)

What are the common drug interactions of Pamidronate Disodium and Doxorubicin Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cardiac arrest
Discomfort
Endocardial fibrosis (cardiac fibrosis refers to an abnormal thickening of the heart valves)
Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Joint contracture (a permanent shortening of a muscle or joint)
Metaplasia (change in the type of adult cells in a tissue to a form abnormal for that tissue)
Mobility decreased (ability to move is reduced)
Myocardial fibrosis (a condition in which the heart's muscle cells are impaired)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

20-29:

n/a

30-39:

Aspergilloma (fungus ball, is a clump of fungus which exists in a body cavity such as the lung)
Asthenia (weakness)
Bone marrow failure
Constipation
Mitral valve incompetence (inefficient heart valve)
Mucosal inflammation (infection of mucous membrane)
Multiple myeloma (cancer of the plasma cells)
Mycobacterium tuberculosis complex test positive
Nausea (feeling of having an urge to vomit)
Night sweats (sweating in night)

40-49:

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Dysphagia (a condition in which swallowing is difficult or painful)
Gamma-glutamyltransferase increased
Hypokalaemia (low potassium)
Laryngitis (inflammation of the larynx)
Leukopenia (less number of white blood cells in blood)
Neutropenia (an abnormally low number of neutrophils)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Sinusitis (inflammation of sinus)
Stomatitis (inflammation of mucous membrane of mouth)

50-59:

n/a

60+:

Depression
Difficulty in walking
Decreased activity
Diabetes mellitus inadequate control
Disease progression
Haemoglobin decreased
Keratitis (eye's cornea, the front part of the eye, becomes inflamed)
Myopathy (a muscular disease in which the muscle fibres do not function)
Osteolysis (dissolution of bone)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 3 people, 15.00%
Breast Cancer: 2 people, 10.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.00%
Renal Osteodystrophy (a bone disease occurs when the kidneys fail to maintain the proper levels of calcium and phosphorus in the blood): 1 person, 5.00%
Nuclear Magnetic Resonance Imaging Brain: 1 person, 5.00%
Metastases To Bone (cancer spreads to bone): 1 person, 5.00%
Medical Device Complication: 1 person, 5.00%
Joint Pain: 1 person, 5.00%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 1 person, 5.00%
Headache (pain in head): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Pamidronate disodium and Doxorubicin hydrochloride?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously