Paracetamol and Marijuana drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paracetamol (acetaminophen) and Marijuana (marijuana). Common drug interactions include muscle spasms among females and balance disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Paracetamol and Marijuana. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.

What is Marijuana?

Marijuana has active ingredients of marijuana. It is often used in stress and anxiety. eHealthMe is studying from 7,397 Marijuana users. Check the latest studies of Marijuana.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

40 people who take Paracetamol and Marijuana together, and have interactions are studied.

Paracetamol and Marijuana drug interactions.

What are the common drug interactions of Paracetamol and Marijuana, by gender? *:

female:

Muscle spasms (muscle contraction)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nervousness
Neutropenia (an abnormally low number of neutrophils)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Night sweats (sweating in night)
Oral candidiasis (fungal infection of mouth)
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
Red blood cell abnormality (abnormal red blood cells)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)

male:

Balance disorder
Blood creatinine decreased
Hallucination (an experience involving the perception of something not present)
Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
Hypoaesthesia (reduced sense of touch or sensation)
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
Insomnia (sleeplessness)
Lymphocyte count decreased
Mobility decreased (ability to move is reduced)
Muscle twitching

What are the common drug interactions of Paracetamol and Marijuana, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Completed suicide (act of taking one's own life)
Cardiac arrest
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)

20-29:

Bradycardia (abnormally slow heart action)
Completed suicide (act of taking one's own life)
Dizziness
Dry throat
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Flushing (the warm, red condition of human skin)
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Loss of consciousness
Lymphocyte count decreased

30-39:

Fungal infection
Hangnail (torn piece of skin next to a fingernail)
Hypertension (high blood pressure)
Infected skin ulcer
Inflammatory marker increased
Lung infection
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment
Mucous stools (mucous with stool)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

40-49:

Lymphocyte count decreased
Mean cell haemoglobin decreased (less than normal haemoglobin per red blood cell in a sample of blood)
Mean cell volume decreased (less of the average red blood cell volume)
Red cell distribution width increased
Urine abnormality
Urine ketone body present
Asthenia (weakness)
Back pain
Blood creatinine decreased
Blood urine present

50-59:

Drug ineffective

60+:

Hypotension (abnormally low blood pressure)
Completed suicide (act of taking one's own life)
Dehydration (dryness resulting from the removal of water)
Febrile neutropenia (fever with reduced white blood cells)
Pulmonary sepsis (pus in lungs)

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 10 people, 25.00%
Suicide Attempt: 3 people, 7.50%
Sleep Disorder: 3 people, 7.50%
Depression: 3 people, 7.50%
Vertebral Artery Occlusion (vertebral artery blockage): 2 people, 5.00%
Stable Angina (a constant chest pain): 2 people, 5.00%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 2 people, 5.00%
Migraine (headache): 2 people, 5.00%
Insomnia (sleeplessness): 2 people, 5.00%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Paracetamol and Marijuana?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously