Paracetamol and Robaxisal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paracetamol (acetaminophen) and Robaxisal (aspirin; methocarbamol). Common drug interactions include asthenia among females and suicide attempt among males.

The phase IV clinical study analyzes what interactions people have when they take Paracetamol and Robaxisal. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.

What is Robaxisal?

Robaxisal has active ingredients of aspirin; methocarbamol. It is often used in back pain. eHealthMe is studying from 223 Robaxisal users. Check the latest studies of Robaxisal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

46 people who take Paracetamol and Robaxisal together, and have interactions are studied.

Paracetamol and Robaxisal drug interactions.

What are the common drug interactions of Paracetamol and Robaxisal, by gender? *:

female:

Asthenia (weakness)

male:

Suicide attempt
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Obesity (having too much body fat)
Respiratory depression (respiration has a rate below 12 breaths)
Victim of child abuse
Child abuse
Dizziness
Nausea (feeling of having an urge to vomit)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Paracetamol and Robaxisal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Drug ineffective
Epidural lipomatosis (excessive accumulation of fat within the epidural space -brain)
Juvenile idiopathic arthritis (a subset of arthritis seen in childhood)
Obesity (having too much body fat)
Respiratory depression (respiration has a rate below 12 breaths)
Victim of child abuse
Child abuse
Dizziness
Nausea (feeling of having an urge to vomit)
Tachypnoea (a condition of rapid breathing over 20 per minute)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Asthenia (weakness)
Blood creatinine increased
Hypercalcaemia (elevated calcium (ca+) level in the blood)

What are the existing conditions these people have? *

Suicide Attempt: 9 people, 19.57%
Sleep Disorder: 5 people, 10.87%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 10.87%
Muscle Spasms (muscle contraction): 5 people, 10.87%
Itching: 5 people, 10.87%
Constipation: 5 people, 10.87%
Child Abuse: 5 people, 10.87%
Stress And Anxiety: 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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