Paracetamol and Selenium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paracetamol (acetaminophen) and Selenium (selenium). Common drug interactions include pancytopenia among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Paracetamol and Selenium. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.

What is Selenium?

Selenium has active ingredients of selenium. It is often used in vitamin supplementation. eHealthMe is studying from 5,314 Selenium users. Check the latest studies of Selenium.



On Jul, 31, 2026

69 people who take Paracetamol and Selenium together, and have interactions are studied.

Paracetamol and Selenium drug interactions.

What are the common drug interactions of Paracetamol and Selenium, by gender? *:

female:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  2. Pathological fracture (broken bone caused by disease)
  3. Rash
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Splenic infarction (tissue damage of spleen)
  6. Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
  7. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  8. Tongue ulceration (ulcers on tongue)
  9. Vision blurred
  10. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

male:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  3. Heart rate increased
  4. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  5. Schizophrenia, paranoid type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect)
  6. Therapeutic response increased (high preventive response)
  7. Urinary tract infection
  8. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  9. Bacterial test positive
  10. Death

What are the common drug interactions of Paracetamol and Selenium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)

20-29:

n/a

30-39:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Proteinuria (presence of protein in the urine)
  3. Respiratory tract infection
  4. Urinary tract infection
  5. Vaginal haemorrhage (vaginal bleeding)
  6. Haemoglobin decreased
  7. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  8. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  9. Metabolic alkalosis (too much bicarbonate in the blood)
  10. Pulmonary embolism (blockage of the main artery of the lung)

40-49:

  1. Stomatitis (inflammation of mucous membrane of mouth)
  2. Anaemia (lack of blood)
  3. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
  4. Adverse reaction
  5. Cardiac flutter (abnormal heart rhythm)
  6. Haematochezia (passage of stools containing blood)
  7. Heart rate increased
  8. Insomnia (sleeplessness)
  9. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  10. Schizophrenia, paranoid type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect)

50-59:

  1. Diarrhoea
  2. Enteritis (inflammation of the small intestine)
  3. Malignant neoplasm progression (cancer tumour came back)
  4. Vomiting
  5. Breast cancer
  6. Fatigue (feeling of tiredness)
  7. Impulse-control disorder
  8. Intentional self-injury
  9. Metastases to central nervous system (cancer spreads to central nervous system)
  10. Suicidal behaviour

60+:

  1. Pain in extremity
  2. Back pain
  3. Leukopenia (less number of white blood cells in blood)
  4. Neuropathy peripheral (surface nerve damage)
  5. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  6. Platelet count decreased
  7. Thrombocytopenia (decrease of platelets in blood)
  8. Vertigo
  9. Alanine aminotransferase increased
  10. Anaemia (lack of blood)

What are the existing conditions these people have? *

  1. Constipation: 9 people, 13.04%
  2. Breast Cancer: 8 people, 11.59%
  3. Urinary Tract Infection: 7 people, 10.14%
  4. Sleep Disorder: 6 people, 8.70%
  5. Stress And Anxiety: 5 people, 7.25%
  6. Joint Pain: 5 people, 7.25%
  7. Diarrhea: 5 people, 7.25%
  8. Depression: 5 people, 7.25%
  9. Nausea (feeling of having an urge to vomit): 4 people, 5.80%
  10. Itching: 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

Do you take Paracetamol and Selenium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Paracetamol and Selenium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paracetamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Selenium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paracetamol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Selenium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen and selenium (the active ingredients of Paracetamol and Selenium, respectively), and Paracetamol and Selenium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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