Paraplatin and Anzemet drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Paraplatin (carboplatin) and Anzemet (dolasetron mesylate). Common drug interactions include drug toxicity among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Paraplatin and Anzemet. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.
What is Paraplatin?
Paraplatin has active ingredients of carboplatin. eHealthMe is studying from 12,392 Paraplatin users. Check the latest studies of Paraplatin.
What is Anzemet?
Anzemet has active ingredients of dolasetron mesylate. eHealthMe is studying from 2,603 Anzemet users. Check the latest studies of Anzemet.
78 people who take Paraplatin and Anzemet together, and have interactions are studied.

What are the common drug interactions of Paraplatin and Anzemet, by gender? *:
female:
- Drug toxicity
- Dry throat
- Erythema (redness of the skin)
- Failure to thrive (inadequate weight gain and physical growth in children)
- Folliculitis (infection of hair root)
- Headache (pain in head)
- Heart rate increased
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
- Lethargy (tiredness)
male:
- Dyspnoea (difficult or laboured respiration)
- Blood pressure decreased
- Lacrimation increased
- Loss of consciousness
- Pain
- Pallor
- Pruritus (severe itching of the skin)
- Urinary incontinence (inability to control the flow of urine and involuntary urination)
- Agitation (state of anxiety or nervous excitement)
- Apnoea (suspension of external breathing)
What are the common drug interactions of Paraplatin and Anzemet, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Alopecia (absence of hair from areas of the body)
- Anxiety
- Emotional distress
- Pain
- Psychological trauma
40-49:
- Vomiting
- Dyspnoea (difficult or laboured respiration)
- Coma (state of unconsciousness lasting more than six hours)
- Death unexplained
- Hypersensitivity
- Nausea (feeling of having an urge to vomit)
- Pruritus (severe itching of the skin)
- Alopecia (absence of hair from areas of the body)
- Anxiety
- Blood pressure decreased
50-59:
- Pruritus (severe itching of the skin)
- Psychological trauma
- Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
- Pyrexia (fever)
- Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
- Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
- Tenderness (pain or discomfort when an affected area is touched)
- Thrombocytopenia (decrease of platelets in blood)
- Tricuspid valve incompetence (inefficient heart valve)
- Weight increased
60+:
- Dyspnoea (difficult or laboured respiration)
- Alopecia (absence of hair from areas of the body)
- Flushing (the warm, red condition of human skin)
- Heart rate irregular
- Hypotension (abnormally low blood pressure)
- Malignant neoplasm progression (cancer tumour came back)
- Oxygen saturation decreased
- Pallor
- Agitation (state of anxiety or nervous excitement)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
What are the existing conditions these people have? *
- Ovarian Cancer (cancer of ovary): 7 people, 8.97%
- Breast Cancer Female: 7 people, 8.97%
- Lung Cancer Stage Unspecified (Excl Metastatic Tumors To Lung): 6 people, 7.69%
- Breast Cancer: 5 people, 6.41%
- Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 5.13%
* Approximation only. Some reports may have incomplete information.
Do you take Paraplatin and Anzemet?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Paraplatin (12,392 reports)
- Anzemet (2,603 reports)
Browse all drug interactions of Paraplatin and Anzemet:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Paraplatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Anzemet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Paraplatin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Anzemet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Zakaria S, Lu KY, Nussenblatt V, Browner I, "Atrial flutter associated with carboplatin administration", Annals of Pharmacotherapy, 2011 Nov .
- Zakaria S, Lu KY, Nussenblatt V, Browner I, "Atrial flutter associated with carboplatin administration", Annals of Pharmacotherapy, 2011 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on carboplatin and dolasetron mesylate (the active ingredients of Paraplatin and Anzemet, respectively), and Paraplatin and Anzemet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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