Paraplatin and Cytotec drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Paraplatin (carboplatin) and Cytotec (misoprostol). Common drug interactions include anaphylactic shock among females and intestinal perforation among males.
The phase IV clinical study analyzes what interactions people have when they take Paraplatin and Cytotec. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Paraplatin?
Paraplatin has active ingredients of carboplatin. eHealthMe is studying from 12,392 Paraplatin users. Check the latest studies of Paraplatin.
What is Cytotec?
Cytotec has active ingredients of misoprostol. It is often used in abortion. eHealthMe is studying from 5,812 Cytotec users. Check the latest studies of Cytotec.
26 people who take Paraplatin and Cytotec together, and have interactions are studied.

What are the common drug interactions of Paraplatin and Cytotec, by gender? *:
female:
- Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
- Eosinophil count increased
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Pleural effusion (water on the lungs)
- Cough
- Pneumonia
- Pyrexia (fever)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Bone marrow failure
- Cardiac failure
male:
- Intestinal perforation (complete penetration of the wall of the intestine)
- Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Blood lactate dehydrogenase increased
- Blood pressure decreased
- Bowel movement irregularity
- C-reactive protein increased
- Chest pain
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
What are the common drug interactions of Paraplatin and Cytotec, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
- Eosinophil count increased
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Pneumonia
- Bone marrow failure
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Alopecia (absence of hair from areas of the body)
- Anxiety
- Dyspnoea (difficult or laboured respiration)
- Emotional distress
50-59:
- Tendon pain
- Cardiac arrest
- Febrile neutropenia (fever with reduced white blood cells)
60+:
- Pleural effusion (water on the lungs)
- Cough
- Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
- Lung adenocarcinoma (a form of non-small cell lung cancer)
- Small intestine ulcer
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Abdominal pain
- Abdominal rigidity
- Abdominal tenderness
- Amyloidosis (a tumour within which amyloid is produced)
What are the existing conditions these people have? *
- Lung Cancer - Non-Small Cell (lung cancer): 11 people, 42.31%
- High Blood Pressure: 8 people, 30.77%
- Pain: 6 people, 23.08%
- Cancer Pain: 5 people, 19.23%
- Lung Adenocarcinoma Metastatic (a form of non-small cell lung cancer spreads to other part): 4 people, 15.38%
- Lung Adenocarcinoma (a form of non-small cell lung cancer): 4 people, 15.38%
- Cough: 4 people, 15.38%
- Lung Neoplasm Malignant (cancer tumour of lung): 3 people, 11.54%
- Constipation: 3 people, 11.54%
- Spinal Column Stenosis (narrowing of spinal column): 2 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Paraplatin and Cytotec?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Paraplatin (12,392 reports)
- Cytotec (5,812 reports)
Browse all drug interactions of Paraplatin and Cytotec:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Paraplatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cytotec:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Paraplatin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cytotec and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Zakaria S, Lu KY, Nussenblatt V, Browner I, "Atrial flutter associated with carboplatin administration", Annals of Pharmacotherapy, 2011 Nov .
- Zakaria S, Lu KY, Nussenblatt V, Browner I, "Atrial flutter associated with carboplatin administration", Annals of Pharmacotherapy, 2011 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on carboplatin and misoprostol (the active ingredients of Paraplatin and Cytotec, respectively), and Paraplatin and Cytotec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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