Paraplatin and Zoledronic drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Paraplatin (carboplatin) and Zoledronic (zoledronic acid). Common drug interactions include constipation among females and decreased appetite among males.
The phase IV clinical study analyzes what interactions people have when they take Paraplatin and Zoledronic. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Paraplatin?
Paraplatin has active ingredients of carboplatin. eHealthMe is studying from 12,392 Paraplatin users. Check the latest studies of Paraplatin.
What is Zoledronic?
Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.
25 people who take Paraplatin and Zoledronic together, and have interactions are studied.

What are the common drug interactions of Paraplatin and Zoledronic, by gender? *:
female:
- Constipation
- Dizziness
- Dry eye (lack of adequate tears)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hypokalaemia (low potassium)
- Muscle spasms (muscle contraction)
- Upper respiratory tract infection
- Hypersensitivity
- Arthralgia (joint pain)
- Diarrhoea
male:
- Decreased appetite
- Nausea (feeling of having an urge to vomit)
- Malignant neoplasm progression (cancer tumour came back)
- Metastases to bone (cancer spreads to bone)
- Neoplasm malignant (cancer tumour)
- Small cell lung cancer metastatic (lung cancer spreads to other body parts)
- Arthralgia (joint pain)
- Back pain
- Blood creatine phosphokinase increased
- Bone marrow failure
What are the common drug interactions of Paraplatin and Zoledronic, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Arthralgia (joint pain)
- Constipation
- Diarrhoea
- Dizziness
- Dry eye (lack of adequate tears)
- Fatigue (feeling of tiredness)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Headache (pain in head)
- Hypersensitivity
- Hypokalaemia (low potassium)
40-49:
n/a
50-59:
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pneumonia
- Pyrexia (fever)
- Alopecia (absence of hair from areas of the body)
- Febrile neutropenia (fever with reduced white blood cells)
- Psychological trauma
60+:
- Decreased appetite
- Nausea (feeling of having an urge to vomit)
- Malignant neoplasm progression (cancer tumour came back)
- Metastases to bone (cancer spreads to bone)
- Neoplasm malignant (cancer tumour)
- Small cell lung cancer metastatic (lung cancer spreads to other body parts)
- Alopecia (absence of hair from areas of the body)
- Back pain
- Blood creatine phosphokinase increased
- Bone marrow failure
What are the existing conditions these people have? *
- Breast Cancer: 14 people, 56.00%
- Joint Pain: 12 people, 48.00%
- Headache (pain in head): 12 people, 48.00%
- Ejection Fraction Decreased (systolic heart failure): 4 people, 16.00%
- Constipation: 3 people, 12.00%
- Breast Cancer Female: 3 people, 12.00%
- Dry Eyes (lack of adequate tears): 2 people, 8.00%
- Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue): 2 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take Paraplatin and Zoledronic?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Paraplatin (12,392 reports)
- Zoledronic (29,812 reports)
Browse all drug interactions of Paraplatin and Zoledronic:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Paraplatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zoledronic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Paraplatin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zoledronic and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Zakaria S, Lu KY, Nussenblatt V, Browner I, "Atrial flutter associated with carboplatin administration", Annals of Pharmacotherapy, 2011 Nov .
- Zakaria S, Lu KY, Nussenblatt V, Browner I, "Atrial flutter associated with carboplatin administration", Annals of Pharmacotherapy, 2011 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on carboplatin and zoledronic acid (the active ingredients of Paraplatin and Zoledronic, respectively), and Paraplatin and Zoledronic (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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