Paricalcitol and Multihance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paricalcitol (paricalcitol) and Multihance (gadobenate dimeglumine). Common drug interactions include nephrogenic systemic fibrosis among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Paricalcitol and Multihance. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Paricalcitol?

Paricalcitol has active ingredients of paricalcitol. eHealthMe is studying from 1,278 Paricalcitol users. Check the latest studies of Paricalcitol.

What is Multihance?

Multihance has active ingredients of gadobenate dimeglumine. eHealthMe is studying from 5,786 Multihance users. Check the latest studies of Multihance.



On Jul, 12, 2026

20 people who take Paricalcitol and Multihance together, and have interactions are studied.

Paricalcitol and Multihance drug interactions.

What are the common drug interactions of Paricalcitol and Multihance, by gender? *:

female:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Joint range of motion decreased (disease of joint movement)
  3. Pain
  4. Oedema peripheral (superficial swelling)
  5. Skin tightness
  6. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  7. Skin hyperpigmentation (disorders affect the colour of your skin)
  8. Deformity (disfigurement)
  9. Skin hypertrophy (skin cells enlarges)
  10. Skin discolouration (change of skin colour)

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Skin tightness
  4. Emotional distress
  5. Joint range of motion decreased (disease of joint movement)
  6. Mobility decreased (ability to move is reduced)
  7. Muscular weakness (muscle weakness)
  8. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  9. Pain
  10. Skin hypertrophy (skin cells enlarges)

What are the common drug interactions of Paricalcitol and Multihance, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Arthralgia (joint pain)
  2. Asthenia (weakness)
  3. Deformity (disfigurement)
  4. Erythema (redness of the skin)
  5. Exfoliative rash (scaly red generalized skin rash)
  6. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  7. Gait disturbance
  8. General physical health deterioration (weak health status)
  9. Joint contracture (a permanent shortening of a muscle or joint)
  10. Joint range of motion decreased (disease of joint movement)

50-59:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Joint range of motion decreased (disease of joint movement)
  3. Deformity (disfigurement)
  4. General physical health deterioration (weak health status)
  5. Skin exfoliation (removal of the oldest dead skin cells)
  6. Skin fibrosis (fibrous tissue formation on skin)
  7. Skin hypertrophy (skin cells enlarges)
  8. Anxiety
  9. Asthenia (weakness)
  10. Emotional distress

60+:

n/a

What are the existing conditions these people have? *

  1. Nuclear Magnetic Resonance Imaging Brain: 13 people, 65.00%
  2. Nuclear Magnetic Resonance Imaging Abdominal: 9 people, 45.00%
  3. Kidney Transplant Rejection: 4 people, 20.00%
  4. Tenderness (pain or discomfort when an affected area is touched): 1 person, 5.00%
  5. Swelling: 1 person, 5.00%
  6. Renal Cell Carcinoma (a kidney cancer): 1 person, 5.00%
  7. Pain: 1 person, 5.00%
  8. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 1 person, 5.00%
  9. Hypotension (abnormally low blood pressure): 1 person, 5.00%
  10. Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Paricalcitol and Multihance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paricalcitol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Multihance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paricalcitol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Multihance and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on paricalcitol and gadobenate dimeglumine (the active ingredients of Paricalcitol and Multihance, respectively), and Paricalcitol and Multihance (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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