Parlodel and Klonopin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Parlodel (bromocriptine mesylate) and Klonopin (clonazepam). Common drug interactions include type 2 diabetes mellitus among females and colon cancer among males.
The phase IV clinical study analyzes what interactions people have when they take Parlodel and Klonopin. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Parlodel?
Parlodel has active ingredients of bromocriptine mesylate. eHealthMe is studying from 2,327 Parlodel users. Check the latest studies of Parlodel.
What is Klonopin?
Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.
17 people who take Parlodel and Klonopin together, and have interactions are studied.

What are the common drug interactions of Parlodel and Klonopin, by gender? *:
female:
- Type 2 diabetes mellitus
- Conjunctival abrasion (injury to outer surface of eye)
- Dizziness
- Exostosis (formation of new bone on the surface of a bone)
- Furuncle (infection of the hair follicle)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Melaena (the passage of black, tarry stools)
- Neck pain
- Neuropathy peripheral (surface nerve damage)
- Otitis externa (external ear infection)
male:
- Colon cancer
- Delusion (a false belief or opinion)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Delirium (wild excitement)
- Depression
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Drug abuse
- Drug dependence
What are the common drug interactions of Parlodel and Klonopin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Depression
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Intraocular pressure increased
- Myopia (difficult to see objects that are far away)
30-39:
- Ill-defined disorder
- Type 2 diabetes mellitus
- Depression
- Suicide attempt
40-49:
- Abdominal pain upper
- Arthralgia (joint pain)
- Bipolar disorder (mood disorder)
- Bradycardia (abnormally slow heart action)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Delirium (wild excitement)
- Depression
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
50-59:
- Conjunctival abrasion (injury to outer surface of eye)
- Dizziness
- Exostosis (formation of new bone on the surface of a bone)
- Furuncle (infection of the hair follicle)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Melaena (the passage of black, tarry stools)
- Neck pain
- Neuropathy peripheral (surface nerve damage)
- Otitis externa (external ear infection)
- Presbyopia (a condition in which the lens of the eye loses its ability to focus, making it difficult to see objects up close)
60+:
- Colon cancer
- Delusion (a false belief or opinion)
- Hallucination (an experience involving the perception of something not present)
- Loss of consciousness
- Murder
- Prostate cancer
- Ankle fracture
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Impaired healing
- Surgery
What are the existing conditions these people have? *
- Parkinson's Disease: 5 people, 29.41%
- Agitation (state of anxiety or nervous excitement): 4 people, 23.53%
- Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 23.53%
- Pain: 4 people, 23.53%
- Insomnia (sleeplessness): 4 people, 23.53%
- Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 23.53%
- Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 3 people, 17.65%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 17.65%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.88%
- Bipolar Disorder (mood disorder): 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Parlodel and Klonopin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Parlodel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Klonopin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Parlodel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Klonopin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on bromocriptine mesylate and clonazepam (the active ingredients of Parlodel and Klonopin, respectively), and Parlodel and Klonopin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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