Parlodel and Mellaril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Parlodel (bromocriptine mesylate) and Mellaril (thioridazine hydrochloride). Common drug interactions include depressed level of consciousness among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Parlodel and Mellaril. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Parlodel?

Parlodel has active ingredients of bromocriptine mesylate. eHealthMe is studying from 2,327 Parlodel users. Check the latest studies of Parlodel.

What is Mellaril?

Mellaril has active ingredients of thioridazine hydrochloride. eHealthMe is studying from 1,516 Mellaril users. Check the latest studies of Mellaril.

On Aug, 03, 2026

17 people who take Parlodel and Mellaril together, and have interactions are studied.

Parlodel and Mellaril drug interactions.

What are the common drug interactions of Parlodel and Mellaril, by gender? *:

female:

Depressed level of consciousness
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Pyrexia (fever)
Conjunctival abrasion (injury to outer surface of eye)
Dizziness
Eating disorder
Exostosis (formation of new bone on the surface of a bone)
Furuncle (infection of the hair follicle)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Melaena (the passage of black, tarry stools)

male:

Hypotension (abnormally low blood pressure)
Abdominal pain upper
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug abuse
Drug dependence
Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
Hypomania (a mild form of mania, marked by elation and hyperactivity)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

What are the common drug interactions of Parlodel and Mellaril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain upper
Arthralgia (joint pain)
Bipolar disorder (mood disorder)
Bradycardia (abnormally slow heart action)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Delirium (wild excitement)
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

50-59:

Conjunctival abrasion (injury to outer surface of eye)
Dizziness
Exostosis (formation of new bone on the surface of a bone)
Furuncle (infection of the hair follicle)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Melaena (the passage of black, tarry stools)
Neck pain
Neuropathy peripheral (surface nerve damage)
Otitis externa (external ear infection)
Otitis media (inflammation of the middle ear)

60+:

Depressed level of consciousness
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Excitability
Haematemesis (vomiting of blood)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Abnormal behaviour
Agitation (state of anxiety or nervous excitement)
Alanine aminotransferase increased
Blood sodium increased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the existing conditions these people have? *

Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 23.53%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 23.53%
Hallucinations (sensations that appear real but are created by your mind): 1 person, 5.88%
Bipolar Disorder (mood disorder): 1 person, 5.88%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 5.88%
Delusion (a false belief or opinion): 1 person, 5.88%
Depression: 1 person, 5.88%
Dyspnea (difficult or laboured breathing): 1 person, 5.88%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 1 person, 5.88%
Stress And Anxiety: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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