1. Home
  2. Analysis
  3. Paroxetine
  4. Bupropion-hydrobromide

Paroxetine and Bupropion hydrobromide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paroxetine (paroxetine hydrochloride) and Bupropion hydrobromide (bupropion hydrobromide). Common drug interactions include weight increased among females.

The phase IV clinical study analyzes what interactions people have when they take Paroxetine and Bupropion hydrobromide. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Paroxetine?

Paroxetine has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 65,088 Paroxetine users. Check the latest studies of Paroxetine.

What is Bupropion hydrobromide?

Bupropion hydrobromide has active ingredients of bupropion hydrobromide. It is often used in depression. eHealthMe is studying from 659 Bupropion hydrobromide users. Check the latest studies of Bupropion hydrobromide.

On Jul, 16, 2026

54 people who take Paroxetine and Bupropion hydrobromide together, and have interactions are studied.

Paroxetine and Bupropion hydrobromide drug interactions.

What are the common drug interactions of Paroxetine and Bupropion Hydrobromide, by gender? *:

female:

  1. Weight increased
  2. Weight decreased
  3. Dysgeusia (disorder of the sense of taste)
  4. Dyspepsia (indigestion)
  5. Feeling hot
  6. Flushing (the warm, red condition of human skin)
  7. Headache (pain in head)
  8. Hostility
  9. Hyperhidrosis (abnormally increased sweating)
  10. Irritability

male:

n/a

What are the common drug interactions of Paroxetine and Bupropion Hydrobromide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Weight increased
  2. Weight decreased
  3. Dysgeusia (disorder of the sense of taste)
  4. Dyspepsia (indigestion)
  5. Feeling hot
  6. Flushing (the warm, red condition of human skin)
  7. Headache (pain in head)
  8. Hostility
  9. Hyperhidrosis (abnormally increased sweating)
  10. Irritability

60+:

n/a

What are the existing conditions these people have? *

  1. Migraine (headache): 30 people, 55.56%
  2. Asthma: 21 people, 38.89%
  3. Pain: 18 people, 33.33%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 11.11%
  5. Hypersensitivity: 3 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Paroxetine and Bupropion hydrobromide?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Paroxetine and Bupropion hydrobromide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paroxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bupropion hydrobromide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paroxetine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bupropion hydrobromide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on paroxetine hydrochloride and bupropion hydrobromide (the active ingredients of Paroxetine and Bupropion hydrobromide, respectively), and Paroxetine and Bupropion hydrobromide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.