Pataday and Ambien drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pataday (olopatadine hydrochloride) and Ambien (zolpidem tartrate). Common drug interactions include infection among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Pataday and Ambien. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Pataday?

Pataday has active ingredients of olopatadine hydrochloride. It is often used in allergies. eHealthMe is studying from 8,288 Pataday users. Check the latest studies of Pataday.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

On Jul, 20, 2026

81 people who take Pataday and Ambien together, and have interactions are studied.

What are the common drug interactions of Pataday and Ambien, by gender? *:

female:

Infection
Infusion site bruising
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Infusion site mass
Osteonecrosis (death of bone)
Pruritus (severe itching of the skin)
Sinusitis (inflammation of sinus)
Skin infection
Somnolence (a state of near-sleep, a strong desire for sleep)
Urinary tract infection

male:

Diarrhoea
Fatigue (feeling of tiredness)
Migraine (headache)
Therapeutic response unexpected
Urinary tract infection
Tendon rupture (tear of tendon)
Acne (skin problems that cause pimples)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Chills (felling of cold)
Chronic kidney disease

What are the common drug interactions of Pataday and Ambien, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Headache (pain in head)
Vitamin d decreased

30-39:

Abdominal pain upper
Acne (skin problems that cause pimples)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Fibromyalgia (a long-term condition which causes pain all over the body)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hepatic enzyme increased
Hepatitis (inflammation of the liver)
Intentional self-injury
Intervertebral disc protrusion (spinal disc protrusion)
Neuralgia (pain in one or more nerves)

40-49:

Bipolar disorder (mood disorder)
Anxiety
Contact lens intolerance (lens associated with irritation and redness of the eye)
Drug ineffective
Dry eye (lack of adequate tears)
Eye inflammation
Hypomania (a mild form of mania, marked by elation and hyperactivity)
Lacrimation increased
Memory impairment
Pain

50-59:

Urinary tract infection
Tendon rupture (tear of tendon)
Abdominal pain upper
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Conjunctivitis (pink eye)
Dyspnoea (difficult or laboured respiration)
Hypersensitivity
Infected cyst
Intervertebral disc protrusion (spinal disc protrusion)

60+:

Diarrhoea
Asthenia (weakness)
Headache (pain in head)
Migraine (headache)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Urinary tract infection
Chills (felling of cold)
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 25 people, 30.86%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 19 people, 23.46%
Asthma: 11 people, 13.58%
Pain: 10 people, 12.35%
High Blood Pressure: 9 people, 11.11%
Stress And Anxiety: 7 people, 8.64%
Immunodeficiency Common Variable: 7 people, 8.64%
High Blood Cholesterol: 7 people, 8.64%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 8.64%
Depression: 6 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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