Pataday and Astelin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pataday (olopatadine hydrochloride) and Astelin (azelastine hydrochloride). Common drug interactions include respiratory tract congestion among females and therapeutic response unexpected among males.

The phase IV clinical study analyzes what interactions people have when they take Pataday and Astelin. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Pataday?

Pataday has active ingredients of olopatadine hydrochloride. It is often used in allergies. eHealthMe is studying from 8,288 Pataday users. Check the latest studies of Pataday.

What is Astelin?

Astelin has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,538 Astelin users. Check the latest studies of Astelin.

On Jul, 18, 2026

37 people who take Pataday and Astelin together, and have interactions are studied.

What are the common drug interactions of Pataday and Astelin, by gender? *:

female:

Respiratory tract congestion (blockage on respiratory system)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Rhinorrhoea (watery mucus discharge from the nose)
Scoliosis (a medical condition in which a person's spine is curved from side to side)
Sinusitis (inflammation of sinus)
Skin discomfort (skin pain/irritation)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Sluggishness (lacking alertness)
Staphylococcal infection (an infection with staphylococcus bacteria)
Swelling

male:

Therapeutic response unexpected
Bruxism (habitual grinding of the teeth, typically during sleep)
Femur fracture
Gallbladder operation
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Hypertension (high blood pressure)
Hysterectomy
Injection site pain
Medical device pain (pain due to medical device)

What are the common drug interactions of Pataday and Astelin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Bruxism (habitual grinding of the teeth, typically during sleep)
Crying
Dyskinesia (abnormality or impairment of voluntary movement)
Emotional distress
Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)
Mania (a state of abnormally elevated or irritable mood)
Cataract (clouding of the lens inside the eye)
Cough
Femur fracture
Gallbladder operation

10-19:

Arthralgia (joint pain)
Asthenia (weakness)
Asthma
Cardiac disorder
Cerebral venous thrombosis (clot in brains venous blood system)
Corneal degeneration (abnormal deposition of substances in the transparent front part of the eye)
Dizziness
Dysstasia (difficulty in standing)
Extrasystoles
Fatigue (feeling of tiredness)

20-29:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hangover
Hypokinesia (decreased bodily movement)
Sluggishness (lacking alertness)

30-39:

n/a

40-49:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Drug ineffective
Pain
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Tooth infection

50-59:

Headache (pain in head)
Drug ineffective
Fall
Neck injury
Visual impairment
Abdominal pain upper
Ageusia (loss of taste functions of the tongue)
Blood pressure increased
Cough
Decreased appetite

60+:

Arthralgia (joint pain)
Asthenia (weakness)
Joint swelling
Muscle spasms (muscle contraction)
Pain in extremity
Pain in jaw
Sleep disorder
Sudden onset of sleep
Visual impairment
Chronic kidney disease

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 24.32%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 21.62%
Asthma: 8 people, 21.62%
Hypersensitivity: 6 people, 16.22%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 10.81%
Osteoporosis (bones weak and more likely to break): 4 people, 10.81%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 8.11%
High Blood Cholesterol: 3 people, 8.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.11%
Partial Seizures (seizures which affect only a part of the brain at onset): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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