Patanase and Enbrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Patanase (olopatadine hydrochloride) and Enbrel (etanercept). Common drug interactions include blood cortisol decreased among females and memory impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Patanase and Enbrel. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Patanase?

Patanase has active ingredients of olopatadine hydrochloride. It is often used in allergies. eHealthMe is studying from 1,514 Patanase users. Check the latest studies of Patanase.

What is Enbrel?

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,678 Enbrel users. Check the latest studies of Enbrel.



On Jul, 13, 2026

27 people who take Patanase and Enbrel together, and have interactions are studied.

Patanase and Enbrel drug interactions.

What are the common drug interactions of Patanase and Enbrel, by gender? *:

female:

  1. Blood cortisol decreased
  2. Clostridial infection (infectious conditions by clostridium bacteria)
  3. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  4. Dyslipidaemia (abnormal amount of lipids)
  5. Exostosis (formation of new bone on the surface of a bone)
  6. Influenza like illness
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  9. Oedema peripheral (superficial swelling)
  10. Pneumonitis (inflammation of the walls of the alveoli in the lungs)

male:

  1. Memory impairment
  2. Sinusitis (inflammation of sinus)
  3. Anaemia (lack of blood)
  4. Anal abscess
  5. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  6. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  7. Nerve block (the interruption of signals travelling along a nerve)
  8. Psoriasis (immune-mediated disease that affects the skin)

What are the common drug interactions of Patanase and Enbrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  2. Nasopharyngitis (inflammation of the nasopharynx)

50-59:

  1. Headache (pain in head)
  2. Sinusitis (inflammation of sinus)
  3. Injection site erythema (redness at injection site)
  4. Lymphadenopathy (disease or enlargement of lymph nodes)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Pain
  7. Pyrexia (fever)
  8. Alopecia (absence of hair from areas of the body)
  9. Arthralgia (joint pain)
  10. Arthropathy

60+:

  1. Memory impairment
  2. Fall
  3. Injection site swelling
  4. Rib fracture
  5. Tooth abscess (pus formation in tooth)
  6. Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
  7. Arthralgia (joint pain)
  8. Breast cancer
  9. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  10. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 4 people, 14.81%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 11.11%
  3. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Patanase and Enbrel?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Patanase and Enbrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Patanase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Enbrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Patanase and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Enbrel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on olopatadine hydrochloride and etanercept (the active ingredients of Patanase and Enbrel, respectively), and Patanase and Enbrel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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