Paxil cr and Lantus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paxil cr (paroxetine hydrochloride) and Lantus (insulin glargine recombinant). Common drug interactions include appendiceal abscess among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Paxil cr and Lantus. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Paxil cr?

Paxil cr has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 8,322 Paxil cr users. Check the latest studies of Paxil cr.

What is Lantus?

Lantus has active ingredients of insulin glargine recombinant. It is often used in diabetes. eHealthMe is studying from 191,782 Lantus users. Check the latest studies of Lantus.



On Jul, 05, 2026

53 people who take Paxil cr and Lantus together, and have interactions are studied.

Paxil cr and Lantus drug interactions.

What are the common drug interactions of Paxil Cr and Lantus, by gender? *:

female:

  1. Appendiceal abscess
  2. Appendicitis (inflammation of the appendix)
  3. Asthma
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Balanitis candida (inflammation of the glands penis by infection with candida albicans)
  6. Blood cholesterol increased
  7. Blood triglycerides increased
  8. Bradycardia (abnormally slow heart action)
  9. Bronchial polyp
  10. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)

male:

  1. Cardiac failure congestive
  2. Aortic valve incompetence
  3. Generalised oedema (swelling all over the body)
  4. Hypoxia (low oxygen in tissues)
  5. Mitral valve disease (disease of mitral valve of heart)
  6. Mitral valve incompetence (inefficient heart valve)
  7. Obstructive airways disorder (a progressive disease that makes it hard to breathe)
  8. Pain
  9. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  10. Premature baby

What are the common drug interactions of Paxil Cr and Lantus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Crying
  2. Derealisation
  3. Diabetic coma
  4. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  5. Dissociation
  6. Feeling of despair
  7. Hair colour changes
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Arrhythmia (irregular heartbeat)
  10. Chest pain

30-39:

  1. Diabetes mellitus inadequate control
  2. Drug ineffective
  3. Hyperglycaemia (high blood sugar)

40-49:

  1. Pneumonia
  2. Abdominal discomfort
  3. Abdominal pain upper
  4. Acute interstitial pneumonitis (acute revere lung disease)
  5. Amnestic disorder (group of disorders that involve loss of memories previously established, loss of the ability to create new memories)
  6. Appendiceal abscess
  7. Appendicitis (inflammation of the appendix)
  8. Asthma
  9. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  10. Back pain

50-59:

  1. Drug ineffective
  2. Swelling face
  3. Anaphylactic reaction (serious allergic reaction)
  4. Chronic kidney disease
  5. Diabetes mellitus inadequate control
  6. Diarrhoea
  7. Hospitalisation
  8. Hypoglycaemia (deficiency of glucose in the bloodstream)
  9. Localised infection (infection at the single location)
  10. Nephrogenic anaemia (anaemia due to kidney disease)

60+:

  1. Hyphaema (collection of blood inside the front part of the eye)
  2. Vitreous haemorrhage (intraocular (inside the eye) bleeding)
  3. Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
  4. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  5. Nausea (feeling of having an urge to vomit)
  6. Pulmonary mass
  7. Arthropathy
  8. Eye disorder
  9. Abnormal dreams
  10. Bronchial polyp

What are the existing conditions these people have? *

  1. Depression: 26 people, 49.06%
  2. High Blood Pressure: 8 people, 15.09%
  3. Postpartum Depression (depression suffered by a mother following childbirth): 7 people, 13.21%
  4. High Blood Cholesterol: 6 people, 11.32%
  5. Type 2 Diabetes: 5 people, 9.43%
  6. Pain: 4 people, 7.55%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 7.55%
  8. Hiv Infection: 4 people, 7.55%
  9. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 5.66%
  10. Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Paxil cr and Lantus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paxil cr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lantus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paxil cr and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lantus and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on paroxetine hydrochloride and insulin glargine recombinant (the active ingredients of Paxil cr and Lantus, respectively), and Paxil cr and Lantus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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