Paxil cr and Ortho tri-cyclen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paxil cr (paroxetine hydrochloride) and Ortho tri-cyclen (ethinyl estradiol; norgestimate). Common drug interactions include crying among females and ascites among males.

The phase IV clinical study analyzes what interactions people have when they take Paxil cr and Ortho tri-cyclen. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Paxil cr?

Paxil cr has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 8,322 Paxil cr users. Check the latest studies of Paxil cr.

What is Ortho tri-cyclen?

Ortho tri-cyclen has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control. eHealthMe is studying from 5,699 Ortho tri-cyclen users. Check the latest studies of Ortho tri-cyclen.

On Jul, 19, 2026

15 people who take Paxil cr and Ortho tri-cyclen together, and have interactions are studied.

Paxil cr and Ortho tri-cyclen drug interactions.

What are the common drug interactions of Paxil Cr and Ortho Tri-Cyclen, by gender? *:

female:

Crying
Agitation (state of anxiety or nervous excitement)
Conversion disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause)
Derealisation
Dissociation
Drug ineffective
Feeling of despair
Hair colour changes
Hypoaesthesia (reduced sense of touch or sensation)
Nausea (feeling of having an urge to vomit)

male:

Ascites (accumulation of fluid in the abdominal cavity)
Cardiomegaly (increased size of heart than normal)
Pleural effusion (water on the lungs)
Skin oedema (swelling of skin)
Cardiac failure
Foetal disorder (fetus disease)
Drug exposure during pregnancy
Hydrops foetalis (fetus characterized by an accumulation of fluid)
Intra-uterine death
Localised oedema (fluid retention in a particular part of the body)

What are the common drug interactions of Paxil Cr and Ortho Tri-Cyclen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Gastric disorder (disease of stomach)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Hyperglycaemia (high blood sugar)
Hyperinsulinaemia (excess levels of insulin circulating in the blood)
Metabolic syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease)
Obesity (having too much body fat)
Weight increased

20-29:

Hair colour changes
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Motion sickness (travel sickness)
Nausea (feeling of having an urge to vomit)
Crying
Agitation (state of anxiety or nervous excitement)
Conversion disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause)
Derealisation
Dissociation

30-39:

Constipation
Drug ineffective
Increased appetite

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Depression: 13 people, 86.67%
Pain: 2 people, 13.33%
Nausea (feeling of having an urge to vomit): 2 people, 13.33%
Multiple Allergies (allergy to multiple agents): 2 people, 13.33%
Irritable Bowel Syndrome: 2 people, 13.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 13.33%
Bladder Spasm: 2 people, 13.33%
Asthma: 2 people, 13.33%
Post-Traumatic Stress Disorder: 1 person, 6.67%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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