Paxlovid and Gemcitabine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paxlovid (nirmatrelvir; ritonavir) and Gemcitabine (gemcitabine). Common drug interactions include colitis among females and cardiac failure among males.

The phase IV clinical study analyzes what interactions people have when they take Paxlovid and Gemcitabine. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Paxlovid?

Paxlovid has active ingredients of nirmatrelvir; ritonavir. eHealthMe is studying from 38,421 Paxlovid users. Check the latest studies of Paxlovid.

What is Gemcitabine?

Gemcitabine has active ingredients of gemcitabine. eHealthMe is studying from 31,337 Gemcitabine users. Check the latest studies of Gemcitabine.

On Jul, 12, 2026

22 people who take Paxlovid and Gemcitabine together, and have interactions are studied.

Paxlovid and Gemcitabine drug interactions.

What are the common drug interactions of Paxlovid and Gemcitabine, by gender? *:

female:

Colitis (inflammation of colon)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

male:

Cardiac failure
Febrile neutropenia (fever with reduced white blood cells)
Aspergillus test positive
Disease progression
Dysgeusia (disorder of the sense of taste)
Pruritus (severe itching of the skin)
Tumour flare (temporary increase in symptoms from a cancer after starting treatment)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)

What are the common drug interactions of Paxlovid and Gemcitabine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dysgeusia (disorder of the sense of taste)
Pruritus (severe itching of the skin)

50-59:

Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Cardiac failure
Tumour flare (temporary increase in symptoms from a cancer after starting treatment)

60+:

Febrile neutropenia (fever with reduced white blood cells)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Colitis (inflammation of colon)

What are the existing conditions these people have? *

Burkitt Lymphoma (cancer of the lymphatic system): 8 people, 36.36%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 22.73%
Lung Disorder (lung disease): 4 people, 18.18%
Nausea (feeling of having an urge to vomit): 2 people, 9.09%
Joint Swelling: 2 people, 9.09%
Joint Pain: 2 people, 9.09%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 9.09%
High Blood Pressure: 2 people, 9.09%
Cardiac Failure: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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