Pazeo and Restasis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pazeo (olopatadine hydrochloride) and Restasis (cyclosporine). Common drug interactions include nausea among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Pazeo and Restasis. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Pazeo?

Pazeo has active ingredients of olopatadine hydrochloride. eHealthMe is studying from 1,256 Pazeo users. Check the latest studies of Pazeo.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

77 people who take Pazeo and Restasis together, and have interactions are studied.

What are the common drug interactions of Pazeo and Restasis, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Fall
Fatigue (feeling of tiredness)
Vomiting
Contusion (a type of hematoma of tissue in which capillaries)
Pruritus (severe itching of the skin)
Diarrhoea
Erythema (redness of the skin)
Headache (pain in head)
Allergy to arthropod sting

male:

Drug ineffective
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Hypertension (high blood pressure)
Ill-defined disorder
Neck injury
Osteoporosis (bones weak and more likely to break)
Pain
Rash
Renal failure (kidney dysfunction)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

What are the common drug interactions of Pazeo and Restasis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Bladder disorder
Blood immunoglobulin e increased
Dehydration (dryness resulting from the removal of water)
Herpes simplex (herpes simplex is a common viral infection)
Human papilloma virus test positive
Pertussis (whooping cough: a disease of the respiratory mucous membrane)
Renal disorder (kidney disease)
Sexually transmitted disease

40-49:

Drug ineffective

50-59:

Cough
Dizziness
Drug hypersensitivity
Ear infection
Eye irritation
Fatigue (feeling of tiredness)
Feeding disorder (when children refuse to eat certain food groups)
Foreign body sensation in eyes (feeling of something in eye)
Hair colour changes
Hair disorder

60+:

Fall
Foot fracture
Abdominal pain lower
Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
Carotid artery disease
Coagulopathy (blood's ability to clot is impaired)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Diarrhoea
Eye pain
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 13 people, 16.88%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 11.69%
High Blood Pressure: 7 people, 9.09%
Pemphigoid (tense blisters on the skin): 6 people, 7.79%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 7.79%
Iridocyclitis (inflammation of the iris and ciliary body of the eye): 6 people, 7.79%
High Blood Cholesterol: 6 people, 7.79%
Nausea (feeling of having an urge to vomit): 5 people, 6.49%
Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 5 people, 6.49%
Pain: 4 people, 5.19%

* Approximation only. Some reports may have incomplete information.

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