Pazeo and Xopenex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pazeo (olopatadine hydrochloride) and Xopenex (levalbuterol hydrochloride). Common drug interactions include diverticulitis among females and constipation among males.
The phase IV clinical study analyzes what interactions people have when they take Pazeo and Xopenex. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.
What is Pazeo?
Pazeo has active ingredients of olopatadine hydrochloride. eHealthMe is studying from 1,256 Pazeo users. Check the latest studies of Pazeo.
What is Xopenex?
Xopenex has active ingredients of levalbuterol hydrochloride. It is often used in asthma. eHealthMe is studying from 13,816 Xopenex users. Check the latest studies of Xopenex.
29 people who take Pazeo and Xopenex together, and have interactions are studied.

What are the common drug interactions of Pazeo and Xopenex, by gender? *:
female:
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Oral fungal infection
- Urinary tract infection
- Diarrhoea
- Migraine (headache)
- Abdominal discomfort
- Adverse drug reaction
- Blood glucose increased
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Headache (pain in head)
male:
- Constipation
- Infection
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
- Pyrexia (fever)
- Vomiting
What are the common drug interactions of Pazeo and Xopenex, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Infection
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
- Pyrexia (fever)
- Vomiting
20-29:
n/a
30-39:
- Abdominal pain upper
- Anaphylactic reaction (serious allergic reaction)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Hypocomplementaemia
- Injection site reaction
- Myalgia (muscle pain)
- Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Swelling
40-49:
- Cystitis (inflammation of the wall of the bladder)
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Infusion site erythema (reddening of the skin at infusion site)
- Injection site erythema (redness at injection site)
- Oral fungal infection
- Polycythaemia vera (blood disorder in which the bone marrow makes too many red blood cells)
- Sinus disorder (disease of sinus)
- Sinusitis (inflammation of sinus)
- Sinusitis fungal (fungal infection of sinus)
- Urinary tract infection
50-59:
- Cystitis (inflammation of the wall of the bladder)
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Oral fungal infection
- Sinus disorder (disease of sinus)
- Sinusitis (inflammation of sinus)
- Sinusitis fungal (fungal infection of sinus)
- Urinary tract infection
- Erythema (redness of the skin)
- Infusion site erythema (reddening of the skin at infusion site)
- Injection site reaction
60+:
- Anxiety
- Arrhythmia (irregular heartbeat)
- Muscular weakness (muscle weakness)
- Oesophageal injury
- Oesophageal stenosis (narrowing of oesophagus)
- Pancreatic carcinoma (pancreatic cancer)
- Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Renal pain (kidney pain)
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 13 people, 44.83%
- Primary Immunodeficiency Syndrome: 7 people, 24.14%
- Sinusitis Fungal (fungal infection of sinus): 5 people, 17.24%
- Sinusitis (inflammation of sinus): 5 people, 17.24%
- Sinus Disorder (disease of sinus): 5 people, 17.24%
- Oral Candidiasis (fungal infection of mouth): 5 people, 17.24%
- Type 2 Diabetes: 3 people, 10.34%
- Parkinson's Disease: 3 people, 10.34%
- Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 3 people, 10.34%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 10.34%
* Approximation only. Some reports may have incomplete information.
Do you take Pazeo and Xopenex?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Pazeo and Xopenex:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pazeo:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Xopenex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pazeo and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Xopenex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on olopatadine hydrochloride and levalbuterol hydrochloride (the active ingredients of Pazeo and Xopenex, respectively), and Pazeo and Xopenex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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