Peg-intron and Lorcet-hd drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Peg-intron (peginterferon alfa-2b) and Lorcet-hd (acetaminophen; hydrocodone bitartrate). Common drug interactions include dysphagia among females.

The phase IV clinical study analyzes what interactions people have when they take Peg-intron and Lorcet-hd. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Peg-intron?

Peg-intron has active ingredients of peginterferon alfa-2b. eHealthMe is studying from 11,142 Peg-intron users. Check the latest studies of Peg-intron.

What is Lorcet-hd?

Lorcet-hd has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 2,221 Lorcet-hd users. Check the latest studies of Lorcet-hd.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 24, 2026

14 people who take Peg-intron and Lorcet-hd together, and have interactions are studied.

Peg-intron and Lorcet-hd drug interactions.

What are the common drug interactions of Peg-Intron and Lorcet-Hd, by gender? *:

female:

  1. Dysphagia (a condition in which swallowing is difficult or painful)
  2. Alopecia (absence of hair from areas of the body)
  3. Injection site rash
  4. Injection site reaction
  5. White blood cell count decreased
  6. Arthralgia (joint pain)
  7. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  8. Nausea (feeling of having an urge to vomit)
  9. Oedema peripheral (superficial swelling)
  10. Stomatitis (inflammation of mucous membrane of mouth)

male:

n/a

What are the common drug interactions of Peg-Intron and Lorcet-Hd, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
  2. Bacterial infection
  3. Cellulitis (infection under the skin)
  4. Constipation
  5. Cough
  6. Crying
  7. Culture wound positive
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Epidermal necrosis (skin condition that is usually caused by a reaction to drugs)
  10. Impaired healing

40-49:

  1. Arthralgia (joint pain)
  2. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  3. Intervertebral disc protrusion (spinal disc protrusion)
  4. Muscular weakness (muscle weakness)
  5. Nerve root compression
  6. Oedema peripheral (superficial swelling)
  7. Radial nerve palsy (paralysis of radial nerve)
  8. Spinal column stenosis (narrowing of spinal column)
  9. Spinal osteoarthritis (joint cartilage loss in spine)
  10. Alopecia (absence of hair from areas of the body)

50-59:

  1. Alopecia (absence of hair from areas of the body)
  2. Dehydration (dryness resulting from the removal of water)
  3. Anger
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Injection site erythema (redness at injection site)
  6. Nausea (feeling of having an urge to vomit)
  7. Throat tightness
  8. Vomiting
  9. Burning sensation
  10. Drug hypersensitivity

60+:

n/a

What are the existing conditions these people have? *

  1. Hepatitis C: 12 people, 85.71%
  2. Hepatitis (inflammation of the liver): 2 people, 14.29%
  3. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Peg-intron and Lorcet-hd?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Peg-intron and Lorcet-hd:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Peg-intron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lorcet-hd:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Peg-intron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lorcet-hd and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on peginterferon alfa-2b and acetaminophen; hydrocodone bitartrate (the active ingredients of Peg-intron and Lorcet-hd, respectively), and Peg-intron and Lorcet-hd (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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