Peg-intron and Sonata drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Peg-intron (peginterferon alfa-2b) and Sonata (zaleplon). Common drug interactions include poor quality sleep among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Peg-intron and Sonata. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Peg-intron?

Peg-intron has active ingredients of peginterferon alfa-2b. eHealthMe is studying from 11,142 Peg-intron users. Check the latest studies of Peg-intron.

What is Sonata?

Sonata has active ingredients of zaleplon. It is often used in insomnia. eHealthMe is studying from 3,330 Sonata users. Check the latest studies of Sonata.



On Jul, 20, 2026

16 people who take Peg-intron and Sonata together, and have interactions are studied.

Peg-intron and Sonata drug interactions.

What are the common drug interactions of Peg-Intron and Sonata, by gender? *:

female:

  1. Poor quality sleep
  2. Rash macular (small, flat red spots)
  3. Abscess (pus)
  4. Activities of daily living impaired
  5. Blood calcium decreased
  6. Erythema (redness of the skin)
  7. Hypokalaemia (low potassium)
  8. Intervertebral disc disorder (spinal disc disorder)
  9. Muscle strain (an injury to a muscle in which the muscle fibres tear)
  10. Swollen tongue (swelling of tongue)

male:

  1. Anaemia (lack of blood)
  2. Blood pressure increased
  3. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  4. Tremor (trembling or shaking movements in one or more parts of your body)
  5. Completed suicide (act of taking one's own life)
  6. Dysphemia (stammering or stuttering)
  7. Hypomania (a mild form of mania, marked by elation and hyperactivity)
  8. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  9. Mania (a state of abnormally elevated or irritable mood)
  10. Overdose

What are the common drug interactions of Peg-Intron and Sonata, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Anaemia (lack of blood)
  2. Renal cell carcinoma stage unspecified (kidney cancer in unknown stage)

10-19:

n/a

20-29:

  1. Hyperthyroidism (over activity of the thyroid gland)
  2. Thyroid disorder (thyroid diseases)
  3. Weight decreased

30-39:

n/a

40-49:

  1. Fatigue (feeling of tiredness)
  2. Fibromyalgia (a long-term condition which causes pain all over the body)
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Joint swelling
  5. Memory impairment
  6. Neuropathy (damage to nerves)
  7. Poor quality sleep
  8. Rash macular (small, flat red spots)
  9. Abscess (pus)
  10. Activities of daily living impaired

50-59:

  1. Anaemia (lack of blood)
  2. Dysgeusia (disorder of the sense of taste)
  3. White blood cell count decreased
  4. Asthenia (weakness)
  5. Dyspnoea (difficult or laboured respiration)
  6. Dyspnoea exertional (breathlessness or shortness of breath)
  7. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  8. Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
  9. Muscular weakness (muscle weakness)
  10. Oral pain

60+:

n/a

What are the existing conditions these people have? *

  1. Hepatitis C: 16 people, 100.00%
  2. Stress And Anxiety: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Peg-intron and Sonata?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Peg-intron and Sonata:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Peg-intron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sonata:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Peg-intron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sonata and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on peginterferon alfa-2b and zaleplon (the active ingredients of Peg-intron and Sonata, respectively), and Peg-intron and Sonata (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: