Pegasys and Cyclophosphamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pegasys (peginterferon alfa 2a) and Cyclophosphamide (cyclophosphamide). Common drug interactions include bone disorder among females and autoimmune neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Pegasys and Cyclophosphamide. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Pegasys?

Pegasys has active ingredients of peginterferon alfa 2a. It is often used in hepatitis c. eHealthMe is studying from 57,446 Pegasys users. Check the latest studies of Pegasys.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.

On Jul, 11, 2026

14 people who take Pegasys and Cyclophosphamide together, and have interactions are studied.

Pegasys and Cyclophosphamide drug interactions.

What are the common drug interactions of Pegasys and Cyclophosphamide, by gender? *:

female:

Bone disorder
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Disease progression
Bone marrow failure
Leukopenia (less number of white blood cells in blood)
Thrombocytopenia (decrease of platelets in blood)
Asthenia (weakness)
Atrioventricular block (heart block)
Dizziness
Fatigue (feeling of tiredness)

male:

Autoimmune neutropenia (autoimmune neutropenia is abnormally low level of neutrophils in the blood)
Drug resistance (reduction in effectiveness of a drug)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Collapse of lung (functional breakdown of lung)
Cough
Death
Decreased appetite
Depression
Dysphonia (speech disorder attributable to a disorder of phonation)
Epistaxis (bleed from the nose)

What are the common drug interactions of Pegasys and Cyclophosphamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Bone marrow failure
Leukopenia (less number of white blood cells in blood)
Thrombocytopenia (decrease of platelets in blood)
Acute myocardial infarction (acute heart attack)
Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
Dizziness
Epistaxis (bleed from the nose)
Hypoaesthesia (reduced sense of touch or sensation)
Pneumonia
Pyrexia (fever)

50-59:

Asthenia (weakness)
Atrioventricular block (heart block)
Fatigue (feeling of tiredness)
Loss of consciousness
Syncope (loss of consciousness with an inability to maintain postural tone)

60+:

Autoimmune neutropenia (autoimmune neutropenia is abnormally low level of neutrophils in the blood)
Drug resistance (reduction in effectiveness of a drug)
Facial paresis (weakness in facial muscle movement)
Fatigue (feeling of tiredness)
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Hepatic congestion (liver congestion)
Iatrogenic injury (iatrogenic injury is a form of medical error)
Insomnia (sleeplessness)
Oesophageal perforation (hole in oesophagus)
Oropharyngeal pain

What are the existing conditions these people have? *

Hepatitis E: 3 people, 21.43%
Extranodal Marginal Zone B-Cell Lymphoma (Malt Type) (cancer originating from b cells in the marginal zone of the malt): 3 people, 21.43%
Type 2 Diabetes: 1 person, 7.14%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 7.14%
Neutropenic Sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection): 1 person, 7.14%
Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 1 person, 7.14%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 7.14%
Malignant Lymphoid Neoplasm (malignant growth or tumour caused by abnormal and uncontrolled cell division in lymph node): 1 person, 7.14%
High Blood Pressure: 1 person, 7.14%
Hepatitis C Virus Test Positive: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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