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Pegasys and Methocarbamol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pegasys (peginterferon alfa 2a) and Methocarbamol (methocarbamol). Common drug interactions include attention deficit/hyperactivity disorder among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Pegasys and Methocarbamol. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Pegasys?

Pegasys has active ingredients of peginterferon alfa 2a. It is often used in hepatitis c. eHealthMe is studying from 57,446 Pegasys users. Check the latest studies of Pegasys.

What is Methocarbamol?

Methocarbamol has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 17,766 Methocarbamol users. Check the latest studies of Methocarbamol.

On Jul, 11, 2026

22 people who take Pegasys and Methocarbamol together, and have interactions are studied.

Pegasys and Methocarbamol drug interactions.

What are the common drug interactions of Pegasys and Methocarbamol, by gender? *:

female:

  1. Attention deficit/hyperactivity disorder
  2. Fatigue (feeling of tiredness)
  3. Platelet count decreased
  4. Aortic occlusion
  5. Memory impairment
  6. Muscular weakness (muscle weakness)
  7. Nuclear magnetic resonance imaging brain
  8. Platelet aggregation increased
  9. Asthenia (weakness)
  10. Cardiovascular disorder (heart diseases)

male:

  1. Fatigue (feeling of tiredness)
  2. Blood glucose increased
  3. Emotional distress
  4. Furuncle (infection of the hair follicle)
  5. Irritability
  6. Procedural complication
  7. Quality of life decreased
  8. Vomiting
  9. White blood cell count decreased
  10. Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Pegasys and Methocarbamol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Chronic kidney disease
  4. Decreased activity
  5. Depression
  6. Diarrhoea
  7. Drug administration error
  8. Dyspnoea (difficult or laboured respiration)
  9. Emotional distress
  10. Fatigue (feeling of tiredness)

50-59:

  1. Attention deficit/hyperactivity disorder
  2. Aortic occlusion
  3. Fatigue (feeling of tiredness)
  4. Memory impairment
  5. Muscular weakness (muscle weakness)
  6. Nuclear magnetic resonance imaging brain
  7. Platelet aggregation increased
  8. Platelet count decreased
  9. Cardiovascular disorder (heart diseases)
  10. Disturbance in attention

60+:

  1. Fatigue (feeling of tiredness)
  2. Arthralgia (joint pain)
  3. Nausea (feeling of having an urge to vomit)
  4. Oropharyngeal pain
  5. Vomiting
  6. Weight decreased
  7. White blood cell count decreased
  8. Asthenia (weakness)
  9. Blood calcium decreased
  10. Decreased appetite

* Approximation only. Some reports may have incomplete information.

Do you take Pegasys and Methocarbamol?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pegasys and Methocarbamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pegasys:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Methocarbamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pegasys and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methocarbamol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on peginterferon alfa 2a and methocarbamol (the active ingredients of Pegasys and Methocarbamol, respectively), and Pegasys and Methocarbamol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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