Peginterferon and Prilosec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Peginterferon (peginterferon alfa-2a; ribavirin) and Prilosec (omeprazole). Common drug interactions include chest discomfort among females and haemoglobin decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Peginterferon and Prilosec. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Peginterferon?

Peginterferon has active ingredients of peginterferon alfa-2a; ribavirin. It is often used in hepatitis c. eHealthMe is studying from 13,778 Peginterferon users. Check the latest studies of Peginterferon.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,286 Prilosec users. Check the latest studies of Prilosec.

On Aug, 06, 2026

56 people who take Peginterferon and Prilosec together, and have interactions are studied.

Peginterferon and Prilosec drug interactions.

What are the common drug interactions of Peginterferon and Prilosec, by gender? *:

female:

Chest discomfort
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cough
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Dizziness
Drug toxicity
Dysgeusia (disorder of the sense of taste)
Dyspepsia (indigestion)
Dysphagia (a condition in which swallowing is difficult or painful)

male:

Haemoglobin decreased
Pulmonary embolism (blockage of the main artery of the lung)
Asthenia (weakness)
Fatigue (feeling of tiredness)
Pyrexia (fever)
Headache (pain in head)
Insomnia (sleeplessness)
Anaemia (lack of blood)
Bradycardia (abnormally slow heart action)
Depression

What are the common drug interactions of Peginterferon and Prilosec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Haemoglobin decreased
Umbilical cord vascular disorder
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Injury
Pain
Psychosomatic disease (situation in which the mind influences the body to create or complicate an illness)
Pulmonary embolism (blockage of the main artery of the lung)
Rash

30-39:

Dizziness
Granulocytopenia (lack of granulocyte)
Nausea (feeling of having an urge to vomit)
Platelet count decreased
Pruritus (severe itching of the skin)

40-49:

Benign breast neoplasm (benign (non-cancerous) tumours of the breast)
Breast cancer
Breast mass
Rash
Decreased appetite
Injection site erythema (redness at injection site)
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Renal failure acute (rapid kidney dysfunction)

50-59:

Oedema peripheral (superficial swelling)
Oral fungal infection
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia
Pruritus (severe itching of the skin)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Pyrexia (fever)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Rectal adenoma (tumour of rectum)
Renal cyst (kidney cyst)

60+:

Decreased appetite
Pyrexia (fever)
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Pancreatitis acute (sudden inflammation of pancreas)
Pneumonia
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)

What are the existing conditions these people have? *

Depression: 7 people, 12.50%
Seasonal Allergy (allergic condition due to certain season): 6 people, 10.71%
High Blood Pressure: 5 people, 8.93%
Diabetes: 5 people, 8.93%
Nausea (feeling of having an urge to vomit): 4 people, 7.14%
Rashes (redness): 3 people, 5.36%
Itching: 3 people, 5.36%
Headache (pain in head): 3 people, 5.36%

* Approximation only. Some reports may have incomplete information.

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