Pemetrexed disodium and Acetylcysteine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pemetrexed disodium (pemetrexed disodium) and Acetylcysteine (acetylcysteine). Common drug interactions include incision site pain among females and intra-abdominal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Pemetrexed disodium and Acetylcysteine. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Pemetrexed disodium?

Pemetrexed disodium has active ingredients of pemetrexed disodium. eHealthMe is studying from 4,270 Pemetrexed disodium users. Check the latest studies of Pemetrexed disodium.

What is Acetylcysteine?

Acetylcysteine has active ingredients of acetylcysteine. It is often used in cough. eHealthMe is studying from 11,563 Acetylcysteine users. Check the latest studies of Acetylcysteine.

On Jul, 17, 2026

18 people who take Pemetrexed disodium and Acetylcysteine together, and have interactions are studied.

Pemetrexed disodium and Acetylcysteine drug interactions.

What are the common drug interactions of Pemetrexed Disodium and Acetylcysteine, by gender? *:

female:

Incision site pain
Renal failure (kidney dysfunction)
Thoracic vertebral fracture
Arteriosclerosis (thickening and hardening of arteries)
Febrile neutropenia (fever with reduced white blood cells)

male:

Intra-abdominal haemorrhage (intra-abdominal bleeding)
Sepsis (a severe blood infection that can lead to organ failure and death)
Malignant neoplasm progression (cancer tumour came back)
Blood lactate dehydrogenase increased
Cardiac arrest
Dehydration (dryness resulting from the removal of water)
Hyperglycaemia (high blood sugar)
Hypotension (abnormally low blood pressure)
Ketoacidosis (high concentrations of ketone bodies in blood)
Platelet count decreased

What are the common drug interactions of Pemetrexed Disodium and Acetylcysteine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Hyperglycaemia (high blood sugar)
Ketoacidosis (high concentrations of ketone bodies in blood)

60+:

Intra-abdominal haemorrhage (intra-abdominal bleeding)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thoracic vertebral fracture
Delirium (wild excitement)
Dyspnoea (difficult or laboured respiration)
Malignant neoplasm progression (cancer tumour came back)
Arteriosclerosis (thickening and hardening of arteries)
Blood lactate dehydrogenase increased
Cardiac arrest
Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 16 people, 88.89%
Pain: 5 people, 27.78%
Infection: 5 people, 27.78%
Vitamin B12 Deficiency: 1 person, 5.56%
Type 2 Diabetes: 1 person, 5.56%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 1 person, 5.56%
Nausea (feeling of having an urge to vomit): 1 person, 5.56%
Insomnia (sleeplessness): 1 person, 5.56%
High Blood Pressure: 1 person, 5.56%
High Blood Cholesterol: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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