Pemetrexed and Amphotericin b drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pemetrexed (pemetrexed) and Amphotericin b (amphotericin b). Common drug interactions include drug intolerance among females and thrombocytopenia among males.
The phase IV clinical study analyzes what interactions people have when they take Pemetrexed and Amphotericin b. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Pemetrexed?
Pemetrexed has active ingredients of pemetrexed. eHealthMe is studying from 17,491 Pemetrexed users. Check the latest studies of Pemetrexed.
What is Amphotericin b?
Amphotericin b has active ingredients of amphotericin b. It is often used in thrush. eHealthMe is studying from 16,275 Amphotericin b users. Check the latest studies of Amphotericin b.
16 people who take Pemetrexed and Amphotericin b together, and have interactions are studied.

What are the common drug interactions of Pemetrexed and Amphotericin B, by gender? *:
female:
- Drug intolerance (drug sensitivity)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Disease progression
- Haemolytic anaemia (anaemia due to haemolysis)
- Oedema (fluid collection in tissue)
male:
- Thrombocytopenia (decrease of platelets in blood)
- Anaemia (lack of blood)
- Febrile neutropenia (fever with reduced white blood cells)
- Hepatic congestion (liver congestion)
- Influenza
- Leukopenia (less number of white blood cells in blood)
- Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
- Death
What are the common drug interactions of Pemetrexed and Amphotericin B, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
- Death
- Flushing (the warm, red condition of human skin)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Disease progression
- Drug intolerance (drug sensitivity)
- Haemolytic anaemia (anaemia due to haemolysis)
- Oedema (fluid collection in tissue)
60+:
- Thrombocytopenia (decrease of platelets in blood)
- Anaemia (lack of blood)
- Febrile neutropenia (fever with reduced white blood cells)
- Hepatic congestion (liver congestion)
- Influenza
- Leukopenia (less number of white blood cells in blood)
- Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Decreased appetite
- Diarrhoea
What are the existing conditions these people have? *
- Lung Cancer - Non-Small Cell (lung cancer): 10 people, 62.50%
- Non-Small Cell Lung Cancer Stage Iv: 4 people, 25.00%
- The Flu (the flu is caused by an influenza virus): 2 people, 12.50%
- Diarrhea: 2 people, 12.50%
- Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 12.50%
- Fungaemia (fungi circulate in the blood): 2 people, 12.50%
- Fever: 2 people, 12.50%
- Dry Eyes (lack of adequate tears): 2 people, 12.50%
- Drug Eruption (adverse drug reaction of the skin): 2 people, 12.50%
- Constipation: 2 people, 12.50%
* Approximation only. Some reports may have incomplete information.
Do you take Pemetrexed and Amphotericin b?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Pemetrexed (17,491 reports)
- Amphotericin b (16,275 reports)
Browse all drug interactions of Pemetrexed and Amphotericin b:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pemetrexed:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Amphotericin b:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pemetrexed and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Amphotericin b and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gota V, Kavathiya K, Doshi K, Gurjar M, Damodaran SE, Noronha V, Joshi A, Prabhash K, "High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy", Cancer management and research, 2017 Jan .
- Gota V, Kavathiya K, Doshi K, Gurjar M, Damodaran SE, Noronha V, Joshi A, Prabhash K, "High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy", Cancer management and research, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on pemetrexed and amphotericin b (the active ingredients of Pemetrexed and Amphotericin b, respectively), and Pemetrexed and Amphotericin b (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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