Pemetrexed and Axitinib drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pemetrexed (pemetrexed) and Axitinib (axitinib). Common drug interactions include pericarditis among females and asthenia among males.
The phase IV clinical study analyzes what interactions people have when they take Pemetrexed and Axitinib. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Pemetrexed?
Pemetrexed has active ingredients of pemetrexed. eHealthMe is studying from 17,491 Pemetrexed users. Check the latest studies of Pemetrexed.
What is Axitinib?
Axitinib has active ingredients of axitinib. eHealthMe is studying from 3,179 Axitinib users. Check the latest studies of Axitinib.
15 people who take Pemetrexed and Axitinib together, and have interactions are studied.
What are the common drug interactions of Pemetrexed and Axitinib, by gender? *:
female:
- Pericarditis (inflammation of the pericardium)
- Pleurisy (inflammation of the pleurae, which causes pain when breathing)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cerebral atrophy (decrement in size of brain)
- Dehydration (dryness resulting from the removal of water)
- Depression
- Left ventricular dysfunction
male:
- Asthenia (weakness)
- Nausea (feeling of having an urge to vomit)
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Vomiting
- Hypertension (high blood pressure)
What are the common drug interactions of Pemetrexed and Axitinib, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Vomiting
- Depression
- Asthenia (weakness)
- Nausea (feeling of having an urge to vomit)
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
50-59:
- Dehydration (dryness resulting from the removal of water)
60+:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cerebral atrophy (decrement in size of brain)
- Hypertension (high blood pressure)
- Left ventricular dysfunction
- Pericarditis (inflammation of the pericardium)
- Pleurisy (inflammation of the pleurae, which causes pain when breathing)
What are the existing conditions these people have? *
- Lung Cancer - Non-Small Cell (lung cancer): 13 people, 86.67%
- Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 8 people, 53.33%
- High Blood Pressure: 2 people, 13.33%
- Neoplasm Malignant (cancer tumour): 1 person, 6.67%
- Insomnia (sleeplessness): 1 person, 6.67%
- Headache (pain in head): 1 person, 6.67%
- Abdominal Discomfort: 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Pemetrexed and Axitinib?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Pemetrexed (17,491 reports)
- Axitinib (3,179 reports)
Browse all drug interactions of Pemetrexed and Axitinib:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pemetrexed:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Axitinib:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pemetrexed and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Axitinib and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gota V, Kavathiya K, Doshi K, Gurjar M, Damodaran SE, Noronha V, Joshi A, Prabhash K, "High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy", Cancer management and research, 2017 Jan .
- Gota V, Kavathiya K, Doshi K, Gurjar M, Damodaran SE, Noronha V, Joshi A, Prabhash K, "High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy", Cancer management and research, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on pemetrexed and axitinib (the active ingredients of Pemetrexed and Axitinib, respectively), and Pemetrexed and Axitinib (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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