Penicillin and Bentyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Penicillin (penicillin g potassium) and Bentyl (dicyclomine hydrochloride). Common drug interactions include pruritus among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Penicillin and Bentyl. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Penicillin?

Penicillin has active ingredients of penicillin g potassium. It is often used in strep throat. eHealthMe is studying from 8,567 Penicillin users. Check the latest studies of Penicillin.

What is Bentyl?

Bentyl has active ingredients of dicyclomine hydrochloride. It is often used in irritable bowel syndrome. eHealthMe is studying from 10,754 Bentyl users. Check the latest studies of Bentyl.

On Jul, 20, 2026

29 people who take Penicillin and Bentyl together, and have interactions are studied.

Penicillin and Bentyl drug interactions.

What are the common drug interactions of Penicillin and Bentyl, by gender? *:

female:

Pruritus (severe itching of the skin)
Respiratory tract infection
Scratch
Urticaria (rash of round, red welts on the skin that itch intensely)
Chronic kidney disease
Dizziness
Nephrogenic anaemia (anaemia due to kidney disease)
Rash
Renal failure (kidney dysfunction)
Arthralgia (joint pain)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Dyspepsia (indigestion)
Loss of consciousness
Peritoneal candidiasis (fungal infection in peritoneal)
Post procedural infection
Renal injury (kidney injury)
Septic shock (shock due to blood infection)
Strabismus (a disorder in which the two eyes do not line up in the same direction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the common drug interactions of Penicillin and Bentyl, by age (0-1 to 60+)? *:

0-1:

Ascites (accumulation of fluid in the abdominal cavity)
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Blood creatinine increased
Candida sepsis (candida in blood stream)
Complications of transplanted kidney
Loss of consciousness
Peritoneal candidiasis (fungal infection in peritoneal)
Post procedural infection
Septic shock (shock due to blood infection)
Strabismus (a disorder in which the two eyes do not line up in the same direction)

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Chronic kidney disease
Dyspepsia (indigestion)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

30-39:

Chronic kidney disease
Dyspepsia (indigestion)
Gastritis (inflammation of stomach)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

40-49:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Depression
Drug effect decreased
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Intestinal obstruction
Joint injury
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)

50-59:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dizziness
Drug hypersensitivity
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Fall
Foot fracture
Impaired gastric emptying
Infusion related reaction
Kidney infection
Limb discomfort (discomfort in leg)

60+:

Chronic kidney disease
Oedema peripheral (superficial swelling)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 44.83%
Pain: 10 people, 34.48%
Stress And Anxiety: 5 people, 17.24%
Depression: 4 people, 13.79%
Migraine (headache): 4 people, 13.79%
Immunodeficiency Common Variable: 4 people, 13.79%
High Blood Pressure: 4 people, 13.79%
Headache (pain in head): 3 people, 10.34%
Infection: 3 people, 10.34%
Indigestion: 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

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