Penicillin and Pradaxa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Penicillin (penicillin g potassium) and Pradaxa (dabigatran etexilate mesylate). Common drug interactions include cerebrovascular accident among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Penicillin and Pradaxa. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Penicillin?

Penicillin has active ingredients of penicillin g potassium. It is often used in strep throat. eHealthMe is studying from 8,567 Penicillin users. Check the latest studies of Penicillin.

What is Pradaxa?

Pradaxa has active ingredients of dabigatran etexilate mesylate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 86,906 Pradaxa users. Check the latest studies of Pradaxa.

On Aug, 02, 2026

23 people who take Penicillin and Pradaxa together, and have interactions are studied.

Penicillin and Pradaxa drug interactions.

What are the common drug interactions of Penicillin and Pradaxa, by gender? *:

female:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Oesophageal varices haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus)
Cerebral haemorrhage (bleeding within the brain)
Coagulopathy (blood's ability to clot is impaired)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
Activated partial thromboplastin time prolonged
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Inflammatory marker increased

male:

Chronic kidney disease
Haematuria (presence of blood in urine)
Cardiac tamponade (fluid accumulates in heart covering)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiogenic shock (inadequate circulation of blood)
Cellulitis of male external genital organ (infection of male genitals soft tissue)
Coagulopathy (blood's ability to clot is impaired)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Death
Delirium (wild excitement)

What are the common drug interactions of Penicillin and Pradaxa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Oesophageal varices haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus)
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Renal failure (kidney dysfunction)

60+:

Coagulopathy (blood's ability to clot is impaired)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Activated partial thromboplastin time prolonged
Anticoagulation drug level above therapeutic
Arteriosclerosis (thickening and hardening of arteries)
Bacterial sepsis
Blood glucose increased
Cardiac tamponade (fluid accumulates in heart covering)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiogenic shock (inadequate circulation of blood)

What are the existing conditions these people have? *

Pain: 5 people, 21.74%
Multiple Myeloma (cancer of the plasma cells): 5 people, 21.74%
High Blood Cholesterol: 4 people, 17.39%
Osteoporosis (bones weak and more likely to break): 3 people, 13.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.04%
Urinary Tract Infection: 2 people, 8.70%
High Blood Pressure: 2 people, 8.70%
Diabetes: 2 people, 8.70%
Blood Pressure Abnormal: 2 people, 8.70%
Anaemia (lack of blood): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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