Penicillin and Soliris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Penicillin (penicillin g potassium) and Soliris (eculizumab). Common drug interactions include dyspnoea among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Penicillin and Soliris. It is created by eHealthMe based on reports of 98 people who take the same drugs from the FDA, and is updated regularly.

What is Penicillin?

Penicillin has active ingredients of penicillin g potassium. It is often used in strep throat. eHealthMe is studying from 8,567 Penicillin users. Check the latest studies of Penicillin.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

On Jul, 13, 2026

98 people who take Penicillin and Soliris together, and have interactions are studied.

Penicillin and Soliris drug interactions.

What are the common drug interactions of Penicillin and Soliris, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Blood lactate dehydrogenase increased
Chills (felling of cold)
Hypertension (high blood pressure)
Swelling face
Arthralgia (joint pain)
Contusion (a type of hematoma of tissue in which capillaries)
Migraine (headache)
Cough
Hypoaesthesia (reduced sense of touch or sensation)

male:

Fatigue (feeling of tiredness)
Blood pressure increased
Biliary tract disorder
Chest discomfort
Chest pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Flatulence (flatus expelled through the anus)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Inflammatory marker increased
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

What are the common drug interactions of Penicillin and Soliris, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Anion gap increased
Aspartate aminotransferase increased
Blood glucose increased
Blood phosphorus decreased
Blood urea decreased
Haematocrit decreased
Haemoglobin decreased
Haptoglobin decreased
Leukaemoid reaction (elevated white blood cell count, or leukocytosis, that is a physiological response to stress or infection)
Specific gravity urine decreased

10-19:

Headache (pain in head)
Nasopharyngitis (inflammation of the nasopharynx)
Oropharyngeal pain
Rhinorrhoea (watery mucus discharge from the nose)
Fatigue (feeling of tiredness)
Sinusitis (inflammation of sinus)
Abdominal pain upper
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)
Dizziness

20-29:

Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Meningococcal sepsis (meningococcal infection to whole body)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Drug ineffective
Hospitalisation
Methylmalonic aciduria (a disorder, passed down through families, in which the body cannot break down certain proteins and fats and result acid in urine)
Renal impairment (severely reduced kidney function)
Blood lactate dehydrogenase increased
Reticulocyte count increased

30-39:

Facial pain
Swelling face
Body temperature increased
Immune system disorder
Pneumonia
Blood lactate dehydrogenase increased
Blood pressure increased
Chills (felling of cold)
Dry skin
Dyspepsia (indigestion)

40-49:

Haematocrit decreased
Reticulocyte count increased
Fungal infection
Neuralgia (pain in one or more nerves)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dyspnoea exertional (breathlessness or shortness of breath)
Eye pain
Headache (pain in head)
Hypersensitivity
Pain

50-59:

Haemoglobin decreased
Abdominal wall haematoma (abdominal wall blood clotting)
Anaemia (lack of blood)
Asthenia (weakness)
Blood albumin decreased
Blood calcium decreased
Blood potassium decreased
Constipation
Dysgeusia (disorder of the sense of taste)
Dyspnoea (difficult or laboured respiration)

60+:

Haemoglobin decreased
Pneumonia
Blood pressure increased
Dizziness
Platelet count decreased
Abdominal distension
Asthenia (weakness)
Cardiac disorder
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depressed mood

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 40 people, 40.82%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 13 people, 13.27%
High Blood Pressure: 9 people, 9.18%

* Approximation only. Some reports may have incomplete information.

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