Penicillin and Xopenex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Penicillin (penicillin g potassium) and Xopenex (levalbuterol hydrochloride). Common drug interactions include thrombosis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Penicillin and Xopenex. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Penicillin?

Penicillin has active ingredients of penicillin g potassium. It is often used in strep throat. eHealthMe is studying from 8,567 Penicillin users. Check the latest studies of Penicillin.

What is Xopenex?

Xopenex has active ingredients of levalbuterol hydrochloride. It is often used in asthma. eHealthMe is studying from 13,816 Xopenex users. Check the latest studies of Xopenex.



On Aug, 05, 2026

40 people who take Penicillin and Xopenex together, and have interactions are studied.

Penicillin and Xopenex drug interactions.

What are the common drug interactions of Penicillin and Xopenex, by gender? *:

female:

  1. Thrombosis (formation of a blood clot inside a blood vessel)
  2. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  3. Upper respiratory tract infection
  4. Vaginal haemorrhage (vaginal bleeding)
  5. Dyspnoea (difficult or laboured respiration)
  6. Chronic kidney disease
  7. Headache (pain in head)
  8. Hypersensitivity
  9. Viral infection
  10. Vision blurred

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Dizziness
  4. Drug hypersensitivity
  5. Dyspnoea (difficult or laboured respiration)
  6. Headache (pain in head)
  7. Hospitalisation
  8. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  9. Pneumonia
  10. Pruritus (severe itching of the skin)

What are the common drug interactions of Penicillin and Xopenex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Confusional state
  3. Epistaxis (bleed from the nose)
  4. Fatigue (feeling of tiredness)
  5. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  6. Headache (pain in head)
  7. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Renal failure (kidney dysfunction)
  10. Respiratory tract infection

50-59:

  1. Chronic kidney disease
  2. Pelvic abscess
  3. Perirectal abscess
  4. Rectal abscess (pus in rectum)
  5. Renal failure (kidney dysfunction)
  6. Renal impairment (severely reduced kidney function)
  7. Gout (uric acid crystals building up in the body)
  8. Nephrogenic anaemia (anaemia due to kidney disease)
  9. Renal ischaemia (lack of blood supply to kidney)
  10. Scrotal gangrene (death of scrotum cells)

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Headache (pain in head)
  4. Hospitalisation
  5. Pruritus (severe itching of the skin)
  6. Rash
  7. Swelling
  8. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  9. Nervousness
  10. Pulmonary oedema (fluid accumulation in the lungs)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 30.00%
  2. Pain: 7 people, 17.50%
  3. Immunodeficiency Common Variable: 5 people, 12.50%
  4. High Blood Pressure: 4 people, 10.00%
  5. Type 2 Diabetes: 4 people, 10.00%
  6. Hypersensitivity: 4 people, 10.00%
  7. Weight Decreased: 3 people, 7.50%
  8. Depression: 3 people, 7.50%
  9. Dyspnea (difficult or laboured breathing): 3 people, 7.50%
  10. Infection: 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Penicillin and Xopenex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Penicillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Xopenex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Penicillin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xopenex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on penicillin g potassium and levalbuterol hydrochloride (the active ingredients of Penicillin and Xopenex, respectively), and Penicillin and Xopenex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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