Pentam and Actrapid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pentam (pentamidine isethionate) and Actrapid (insulin). Common drug interactions include anaemia among females and colitis among males.
The phase IV clinical study analyzes what interactions people have when they take Pentam and Actrapid. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Pentam?
Pentam has active ingredients of pentamidine isethionate. eHealthMe is studying from 5,686 Pentam users. Check the latest studies of Pentam.
What is Actrapid?
Actrapid has active ingredients of insulin. eHealthMe is studying from 4,864 Actrapid users. Check the latest studies of Actrapid.
13 people who take Pentam and Actrapid together, and have interactions are studied.

What are the common drug interactions of Pentam and Actrapid, by gender? *:
female:
- Anaemia (lack of blood)
- Bleeding time prolonged
- Colon cancer
- Headache (pain in head)
- Hydronephrosis (water inside the kidney)
- Hypertension (high blood pressure)
- Leukopenia (less number of white blood cells in blood)
- Pyrexia (fever)
- Ureteric obstruction
- Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
male:
- Colitis (inflammation of colon)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Pyrexia (fever)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Hepatitis (inflammation of the liver)
- Lower respiratory tract infection
- Thrombocytopenia (decrease of platelets in blood)
- Blood creatine phosphokinase increased
- Dyspnoea (difficult or laboured respiration)
- Night sweats (sweating in night)
What are the common drug interactions of Pentam and Actrapid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Colitis (inflammation of colon)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Hepatitis (inflammation of the liver)
- Lower respiratory tract infection
- Thrombocytopenia (decrease of platelets in blood)
- Platelet count decreased
50-59:
- Anaemia (lack of blood)
- Bleeding time prolonged
- Post transplant lymphoproliferative disorder
- Epstein-barr virus associated lymphoproliferative disorder (lymphocytes are produced in excessive quantities associated with epstein-barr virus)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Squamous cell carcinoma (a cancer of a kind of epithelial cell)
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Colon cancer
- Headache (pain in head)
60+:
n/a
What are the existing conditions these people have? *
- Hypervolaemia (abnormally increased volume of blood): 4 people, 30.77%
- Rashes (redness): 4 people, 30.77%
- Agitation Postoperative: 4 people, 30.77%
- Neutropenic Colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition): 4 people, 30.77%
- Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 4 people, 30.77%
- Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 4 people, 30.77%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 30.77%
- Hypercalcaemia (elevated calcium (ca+) level in the blood): 4 people, 30.77%
- High Blood Pressure: 4 people, 30.77%
- Blood Calcium Increased: 3 people, 23.08%
* Approximation only. Some reports may have incomplete information.
Do you take Pentam and Actrapid?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Pentam and Actrapid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pentam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Actrapid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pentam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Actrapid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pentamidine isethionate and insulin (the active ingredients of Pentam and Actrapid, respectively), and Pentam and Actrapid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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