Pentam and Ramelteon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pentam (pentamidine isethionate) and Ramelteon (ramelteon). Common drug interactions include abdominal pain among females and oesophagitis among males.

The phase IV clinical study analyzes what interactions people have when they take Pentam and Ramelteon. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Pentam?

Pentam has active ingredients of pentamidine isethionate. eHealthMe is studying from 5,686 Pentam users. Check the latest studies of Pentam.

What is Ramelteon?

Ramelteon has active ingredients of ramelteon. It is often used in insomnia. eHealthMe is studying from 1,387 Ramelteon users. Check the latest studies of Ramelteon.

On Jul, 15, 2026

17 people who take Pentam and Ramelteon together, and have interactions are studied.

What are the common drug interactions of Pentam and Ramelteon, by gender? *:

female:

Abdominal pain
Blood lactate dehydrogenase increased
Diarrhoea
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Renal failure (kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
Thrombotic thrombocytopenic purpura (a rare blood disorder characterized by clotting in small blood vessels of the body)

male:

Oesophagitis (inflammation of oesophagus)
Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
Pulmonary alveolar haemorrhage (acute bleeding)
Skin exfoliation (removal of the oldest dead skin cells)
Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Cholecystitis acute (rapid infection of gallbladder)
Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time)
Gastrointestinal mucosal exfoliation (mucous membrane comes out and new takes place in gastrointestinal tract)
Haematemesis (vomiting of blood)

What are the common drug interactions of Pentam and Ramelteon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Oesophagitis (inflammation of oesophagus)
Skin exfoliation (removal of the oldest dead skin cells)
Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time)
Gastrointestinal mucosal exfoliation (mucous membrane comes out and new takes place in gastrointestinal tract)
Haematemesis (vomiting of blood)
Oesophageal haemorrhage (bleeding from oesophagus)

30-39:

n/a

40-49:

Cholecystitis acute (rapid infection of gallbladder)
Pulmonary alveolar haemorrhage (acute bleeding)

50-59:

n/a

60+:

Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
Abdominal pain
Blood lactate dehydrogenase increased
Diarrhoea
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Renal failure (kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
Thrombotic thrombocytopenic purpura (a rare blood disorder characterized by clotting in small blood vessels of the body)

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 23.53%
Constipation: 3 people, 17.65%
Venoocclusive Liver Disease (small veins in the liver are obstructed): 3 people, 17.65%
Bone Marrow Conditioning Regimen: 2 people, 11.76%
T-Cell Type Acute Leukaemia (a form of cancer of the white blood cells): 2 people, 11.76%
Dry Skin: 2 people, 11.76%
Mantle Cell Lymphoma Refractory (relapsed cancer of lymphocytes, a type of white blood cell): 2 people, 11.76%
Mantle Cell Lymphoma Recurrent (cancer of lymphocytes, a type of white blood cell- recurrent): 2 people, 11.76%
Erosive Oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time): 2 people, 11.76%
Skin Infection: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Pentam and Ramelteon?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously