Pentam and Valsartan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pentam (pentamidine isethionate) and Valsartan (valsartan). Common drug interactions include cataract among females and neuropathy peripheral among males.
The phase IV clinical study analyzes what interactions people have when they take Pentam and Valsartan. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Pentam?
Pentam has active ingredients of pentamidine isethionate. eHealthMe is studying from 5,686 Pentam users. Check the latest studies of Pentam.
What is Valsartan?
Valsartan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 63,805 Valsartan users. Check the latest studies of Valsartan.
26 people who take Pentam and Valsartan together, and have interactions are studied.

What are the common drug interactions of Pentam and Valsartan, by gender? *:
female:
- Cataract (clouding of the lens inside the eye)
- Constipation
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Dry mouth
- Dry skin
- Fatigue (feeling of tiredness)
- Ingrowing nail
- Insomnia (sleeplessness)
- Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
male:
- Neuropathy peripheral (surface nerve damage)
- Fall
- Fatigue (feeling of tiredness)
- Hearing impaired
- Hyporeflexia (a condition of below normal or absent reflexes)
- Liver injury
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
- Rash
- Renal failure (kidney dysfunction)
- Urticaria (rash of round, red welts on the skin that itch intensely)
What are the common drug interactions of Pentam and Valsartan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Death
- Spinal column injury (spinal cord bone injury)
- Spinal cord injury
- Chronic kidney disease
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Renal tubular necrosis (death of kidney tubules)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
50-59:
- Fall
- Hip fracture
- Neuropathy peripheral (surface nerve damage)
- Cataract (clouding of the lens inside the eye)
- Constipation
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Dry mouth
- Dry skin
- Fatigue (feeling of tiredness)
60+:
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
- Neutropenia (an abnormally low number of neutrophils)
- Liver injury
- Neuropathy peripheral (surface nerve damage)
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
- Purpura (purplish discoloration of the skin)
- Renal failure (kidney dysfunction)
- Venoocclusive liver disease (small veins in the liver are obstructed)
- White blood cell count decreased
- Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
What are the existing conditions these people have? *
- Blood Pressure Abnormal: 6 people, 23.08%
- Stress And Anxiety: 6 people, 23.08%
- Diabetes: 6 people, 23.08%
- Pain: 6 people, 23.08%
- Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 6 people, 23.08%
- Insomnia (sleeplessness): 6 people, 23.08%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 19.23%
- High Blood Cholesterol: 5 people, 19.23%
- Hepatitis B: 4 people, 15.38%
- Histoplasmosis Disseminated (respiratory infection caused by inhaling the spores of the fungus histoplasma capsulatum): 4 people, 15.38%
* Approximation only. Some reports may have incomplete information.
Do you take Pentam and Valsartan?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Pentam and Valsartan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pentam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Valsartan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pentam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Valsartan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pentamidine isethionate and valsartan (the active ingredients of Pentam and Valsartan, respectively), and Pentam and Valsartan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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