Pentasa and Para drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pentasa (mesalamine) and Para (para - aminobenzoic acid (paba)). Common drug interactions include mucous stools among females and inflammatory bowel disease among males.

The phase IV clinical study analyzes what interactions people have when they take Pentasa and Para. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Pentasa?

Pentasa has active ingredients of mesalamine. It is often used in crohn's disease. eHealthMe is studying from 23,325 Pentasa users. Check the latest studies of Pentasa.

What is Para?

Para has active ingredients of para - aminobenzoic acid (paba). eHealthMe is studying from 2,194 Para users. Check the latest studies of Para.

On Jul, 28, 2026

68 people who take Pentasa and Para together, and have interactions are studied.

What are the common drug interactions of Pentasa and Para, by gender? *:

female:

Mucous stools (mucous with stool)
Nausea (feeling of having an urge to vomit)
Oral candidiasis (fungal infection of mouth)
Oxygen saturation decreased
Peripheral swelling
Proctalgia (pain in the rectum)
Rectal haemorrhage (bleeding from anus)
Renal impairment (severely reduced kidney function)
Vaginal discharge
Vitamin d deficiency

male:

Inflammatory bowel disease
Frequent bowel movements
Ulcer
Weight increased
Adverse drug reaction
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Haematochezia (passage of stools containing blood)
Impaired work ability
Rash

What are the common drug interactions of Pentasa and Para, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Drug ineffective
Heart rate increased
Pyrexia (fever)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

20-29:

Inflammatory bowel disease
Depressed mood
Drug level above therapeutic
Feeling jittery
Urinary tract infection
Blood pressure fluctuation
Blood pressure increased
Weight decreased
Confusional state
Drug dependence

30-39:

Drug ineffective
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Somnolence (a state of near-sleep, a strong desire for sleep)

40-49:

Abdominal discomfort
Blood pressure fluctuation
Chest discomfort
Chills (felling of cold)
Drug level below therapeutic
Fatigue (feeling of tiredness)
Heart rate irregular
Lung disorder (lung disease)
Malaise (a feeling of general discomfort or uneasiness)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

50-59:

Drug ineffective
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthma
Chronic kidney disease
Depression
Drug intolerance (drug sensitivity)
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
Hypertension (high blood pressure)
Migraine (headache)
Psoriasis (immune-mediated disease that affects the skin)

60+:

Drug ineffective
Oedema peripheral (superficial swelling)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Dyspnoea (difficult or laboured respiration)
Eating disorder
Flushing (the warm, red condition of human skin)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrointestinal pain
Heart rate irregular
Incoherent (talking in a confused and unclear way)

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 46 people, 67.65%
Nausea (feeling of having an urge to vomit): 11 people, 16.18%
High Blood Pressure: 9 people, 13.24%
Migraine (headache): 5 people, 7.35%

* Approximation only. Some reports may have incomplete information.

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