Pentasa and Vancomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pentasa (mesalamine) and Vancomycin (vancomycin). Common drug interactions include neutropenic sepsis among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Pentasa and Vancomycin. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Pentasa?

Pentasa has active ingredients of mesalamine. It is often used in crohn's disease. eHealthMe is studying from 23,325 Pentasa users. Check the latest studies of Pentasa.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.

On Jul, 06, 2026

71 people who take Pentasa and Vancomycin together, and have interactions are studied.

Pentasa and Vancomycin drug interactions.

What are the common drug interactions of Pentasa and Vancomycin, by gender? *:

female:

Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Arthralgia (joint pain)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Diarrhoea
Bone pain
C-reactive protein increased
Cancer pain
Mucosal inflammation (infection of mucous membrane)
Oedema peripheral (superficial swelling)
Vomiting

male:

Diarrhoea
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Hypersensitivity
Otitis externa (external ear infection)
Malaise (a feeling of general discomfort or uneasiness)
Pyrexia (fever)
Rash
Ascites (accumulation of fluid in the abdominal cavity)
Blood urea decreased
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

What are the common drug interactions of Pentasa and Vancomycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Drug ineffective
Haematochezia (passage of stools containing blood)

10-19:

n/a

20-29:

Anal fissure
Abdominal pain
Drug ineffective
Dizziness
Palpitations (feelings or sensations that your heart is pounding or racing)

30-39:

n/a

40-49:

n/a

50-59:

Alanine aminotransferase increased
Blood pressure increased
Cystitis bacterial (inflammation of the wall of the bladder by bacteria escherichia coli)
Diarrhoea
Drug level below therapeutic
Gilbert's syndrome (liver condition in which the liver doesn't properly process a substance called bilirubin)
Hyperthyroidism (over activity of the thyroid gland)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Intestinal resection
Sinus congestion (blockage of sinus)

60+:

Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Diarrhoea
Wound
Disease progression
Oedema (fluid collection in tissue)
Pain in extremity
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Neutropenia (an abnormally low number of neutrophils)

What are the existing conditions these people have? *

Dry Skin: 26 people, 36.62%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 25 people, 35.21%
Wound: 22 people, 30.99%
Joint Pain: 22 people, 30.99%
Breast Cancer Metastatic: 22 people, 30.99%
Cellulitis (infection under the skin): 22 people, 30.99%
Fever: 22 people, 30.99%
Urinary Tract Infection: 22 people, 30.99%
Abdominal Hernia Obstructive (abdominal hernia causing a blockage): 22 people, 30.99%
Oedema Peripheral (superficial swelling): 22 people, 30.99%

* Approximation only. Some reports may have incomplete information.

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