Pentazocine and Propofol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pentazocine (pentazocine hydrochloride) and Propofol (propofol). Common drug interactions include accelerated idioventricular rhythm among females and arteriospasm coronary among males.

The phase IV clinical study analyzes what interactions people have when they take Pentazocine and Propofol. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Pentazocine?

Pentazocine has active ingredients of pentazocine hydrochloride. eHealthMe is studying from 741 Pentazocine users. Check the latest studies of Pentazocine.

What is Propofol?

Propofol has active ingredients of propofol. It is often used in colonoscopy abnormal. eHealthMe is studying from 38,224 Propofol users. Check the latest studies of Propofol.

On Jul, 11, 2026

36 people who take Pentazocine and Propofol together, and have interactions are studied.

Pentazocine and Propofol drug interactions.

What are the common drug interactions of Pentazocine and Propofol, by gender? *:

female:

Accelerated idioventricular rhythm (rate of cardiac contraction)
Gastric haemorrhage (bleeding stomach)
Hepatic cyst infection
Loss of consciousness
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Abortion missed (delayed or silent miscarriage)
Abortion spontaneous (naturally occurring miscarriage)
Abortion threatened (abortion with vaginal bleeding)
Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
Ascites (accumulation of fluid in the abdominal cavity)

male:

Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
Renal impairment (severely reduced kidney function)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Atrioventricular block second degree (heart block second degree)
Bradyarrhythmia (heart slowness)
Facial paralysis (loss of function of face muscle)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Loss of consciousness
Sinus bradycardia (an unusually slow heartbeat due to heart disease)

What are the common drug interactions of Pentazocine and Propofol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anaphylactic reaction (serious allergic reaction)
Bradyarrhythmia (heart slowness)
Cardiac arrest

20-29:

Cardiac arrest
Hyperthermia malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Sinus bradycardia (an unusually slow heartbeat due to heart disease)

30-39:

Abortion threatened (abortion with vaginal bleeding)
Maternal exposure during pregnancy (use of substance during pregnancy)
Metrorrhagia (uterine bleeding at irregular intervals)
Vulvovaginal pruritus (vulvovaginal severe itching)

40-49:

Accelerated idioventricular rhythm (rate of cardiac contraction)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

50-59:

Bradycardia (abnormally slow heart action)
Hypotension (abnormally low blood pressure)
Facial paralysis (loss of function of face muscle)
Hypokalaemia (low potassium)
Loss of consciousness
Thrombocytosis

60+:

Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
Renal impairment (severely reduced kidney function)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Ascites (accumulation of fluid in the abdominal cavity)
Atrioventricular block (heart block)
Atrioventricular block second degree (heart block second degree)
Bradycardia (abnormally slow heart action)
Circulatory collapse
Depressed level of consciousness

What are the existing conditions these people have? *

Sedation: 11 people, 30.56%
High Blood Pressure: 5 people, 13.89%
Pain: 3 people, 8.33%
General Anaesthesia: 3 people, 8.33%
Cardiac Failure: 3 people, 8.33%
Stress And Anxiety: 2 people, 5.56%
Pneumonia Staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus): 2 people, 5.56%
Neuromuscular Blockade Reversal: 2 people, 5.56%
Neuromuscular Blockade: 2 people, 5.56%
Nausea (feeling of having an urge to vomit): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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