Pentoxifylline and Rituxan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pentoxifylline (pentoxifylline) and Rituxan (rituximab). Common drug interactions include squamous cell carcinoma of skin among females and skin ulcer among males.

The phase IV clinical study analyzes what interactions people have when they take Pentoxifylline and Rituxan. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Pentoxifylline?

Pentoxifylline has active ingredients of pentoxifylline. eHealthMe is studying from 5,997 Pentoxifylline users. Check the latest studies of Pentoxifylline.

What is Rituxan?

Rituxan has active ingredients of rituximab. It is often used in rheumatoid arthritis. eHealthMe is studying from 64,791 Rituxan users. Check the latest studies of Rituxan.

On Aug, 03, 2026

24 people who take Pentoxifylline and Rituxan together, and have interactions are studied.

Pentoxifylline and Rituxan drug interactions.

What are the common drug interactions of Pentoxifylline and Rituxan, by gender? *:

female:

Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
Mouth ulceration (mouth ulcers)
Neutropenia (an abnormally low number of neutrophils)
Skin cancer
Accidental exposure
Anaemia (lack of blood)
Nausea (feeling of having an urge to vomit)
Renal failure (kidney dysfunction)
Aphthous stomatitis (mouth ulcer)
Leukopenia (less number of white blood cells in blood)

male:

Skin ulcer
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Oral candidiasis (fungal infection of mouth)
Osteoporosis (bones weak and more likely to break)
Oxygen saturation decreased
Pneumonia
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Pulmonary function test decreased
Rales (an abnormal respiratory sound characterized by fine crackles)
Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)

What are the common drug interactions of Pentoxifylline and Rituxan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Herpes zoster
Palpitations (feelings or sensations that your heart is pounding or racing)
Weight increased
Rash
Mouth ulceration (mouth ulcers)
Neutropenia (an abnormally low number of neutrophils)
Asthenia (weakness)

50-59:

Cough
Diastolic dysfunction
Dyspnoea (difficult or laboured respiration)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haematuria (presence of blood in urine)
Localised infection (infection at the single location)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Oesophageal dilatation (enlarged oesophagus)
Oral candidiasis (fungal infection of mouth)
Osteoporosis (bones weak and more likely to break)

60+:

Fall
Foreign body in eye (foreign particle in eye)
Head injury
Lacrimation increased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Device dislocation
Infusion related reaction
Nausea (feeling of having an urge to vomit)
On and off phenomenon

What are the existing conditions these people have? *

Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 6 people, 25.00%
Interstitial Lung Disease: 6 people, 25.00%
Behcet's Syndrome (involves inflammation of the blood vessels): 6 people, 25.00%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 3 people, 12.50%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 3 people, 12.50%
Immunodeficiency Common Variable: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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