Pepcid ac and Lopid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid ac (famotidine) and Lopid (gemfibrozil). Common drug interactions include balance disorder among females and acute myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Pepcid ac and Lopid. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid ac?

Pepcid ac has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,573 Pepcid ac users. Check the latest studies of Pepcid ac.

What is Lopid?

Lopid has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 9,700 Lopid users. Check the latest studies of Lopid.



On Jul, 07, 2026

11 people who take Pepcid ac and Lopid together, and have interactions are studied.

Pepcid ac and Lopid drug interactions.

What are the common drug interactions of Pepcid Ac and Lopid, by gender? *:

female:

  1. Balance disorder
  2. Fatigue (feeling of tiredness)
  3. Arthralgia (joint pain)
  4. Arthropathy
  5. Asthenia (weakness)
  6. Ataxia (loss of full control of bodily movements)
  7. Bone disorder
  8. Constipation
  9. Drug hypersensitivity
  10. Gait disturbance

male:

  1. Acute myocardial infarction (acute heart attack)
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Ataxia (loss of full control of bodily movements)
  4. Balance disorder
  5. Bladder disorder
  6. Fatigue (feeling of tiredness)
  7. Gait disturbance
  8. Hypertension (high blood pressure)
  9. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  10. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

What are the common drug interactions of Pepcid Ac and Lopid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Arthralgia (joint pain)
  2. Asthenia (weakness)
  3. Ataxia (loss of full control of bodily movements)
  4. Balance disorder
  5. Fatigue (feeling of tiredness)
  6. Gait disturbance
  7. Hypertension (high blood pressure)
  8. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  9. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  10. Muscular weakness (muscle weakness)

50-59:

  1. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  2. Ventricular dysfunction (heart dysfunction)
  3. Chronic kidney disease
  4. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  5. Polytraumatism (multiple trauma)
  6. Acute myocardial infarction (acute heart attack)
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  9. Sinus disorder (disease of sinus)

60+:

  1. Constipation
  2. Drug hypersensitivity
  3. Headache (pain in head)
  4. Impaired healing
  5. Wound complication
  6. Wound secretion

What are the existing conditions these people have? *

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 18.18%
  2. High Blood Pressure: 2 people, 18.18%
  3. Pain: 2 people, 18.18%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 18.18%
  5. Blood Disorder: 1 person, 9.09%
  6. Blood Iron Decreased: 1 person, 9.09%
  7. Breast Cancer Metastatic: 1 person, 9.09%
  8. Cardiac Disorder: 1 person, 9.09%
  9. Cardiac Failure Congestive: 1 person, 9.09%
  10. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Pepcid ac and Lopid?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pepcid ac and Lopid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pepcid ac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lopid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pepcid ac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lopid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on famotidine and gemfibrozil (the active ingredients of Pepcid ac and Lopid, respectively), and Pepcid ac and Lopid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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